ID   PHK_BRUA2               Reviewed;         789 AA.
AC   Q2YK44;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=BAB2_0836;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; AM040265; CAJ13002.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q2YK44; -.
DR   SMR; Q2YK44; -.
DR   STRING; 359391.BAB2_0836; -.
DR   EnsemblBacteria; CAJ13002; CAJ13002; BAB2_0836.
DR   KEGG; bmf:BAB2_0836; -.
DR   HOGENOM; CLU_013954_2_0_5; -.
DR   OMA; LSTMDHC; -.
DR   Proteomes; UP000002719; Chromosome II.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..789
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_1000068387"
SQ   SEQUENCE   789 AA;  89240 MW;  2EC05CC39624D7B3 CRC64;
     MPAKGPLTPQ QLSLINRYWR AANYLSVGQI YLMKNPLLRE PLQPEHIKPR LLGHWGTTPG
     LNFIYAHLNR IIQQRNANVI YICGPGHGGP GMVANTYLEG TYSEIYPAIS EDEAGMERLF
     RQFSFPGGIP SHAAPETPGS IHEGGELGYA LVHAYGAAFD NPDLVVACVV GDGEAETGAL
     ATSWHSNKFL NPARDGAVLP ILHLNGYKIA NPTVLARLSD DDLDNLFRGY GYEPFFVEGS
     EPADMHQKMA ATLDTIFQRI QDIKKNADVH SPERPRWPMI ILRSPKGWTG PKTVDGLVVE
     NYWRAHEVPV ANCRENDAHR KILEDWMKSY DPSDLFDEKG ALKPELRALA PKGEARIGAN
     PHANGGLLRK ELHMPDFRQY AVNVTEPGAI EAQSTKILGD FLRDVMKLNE TEKNFRIFGP
     DETASNRLGS VLEATNRVWM AETLDMDDHL AADGRVMEVL SEHLCQGWLE GYLLSGRHGF
     FSCYEAFIHI IDSMFNQHAK WLQVARELEW RKPISSLNYL LTSHVWRQDH NGFSHQDPGF
     VDLVANKSAD IARVYFPPDA NTLLWVGDHC LKTWNRVNVI VAGKQPEPQW LTMAEAEKHC
     EAGLGIWEWA GTEDGLEPDI VMACAGDVPT METLAAVDLL RQSLPHLRIR VVNVVDLMVL
     QSPHQHPHGI SDEEFDRMFT TNRPVIFAYH GYPYLIHRLV YKRTNHSNFH VRGFIEQGTT
     TTPFDMTVLN ELDRFHLAME AVERLPLGES VAKPLIDNFT EKLALHKDYI RQHGEDMPEI
     RDWKWTWPR