ID   PHK_NITEU               Reviewed;         790 AA.
AC   Q82T07;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=NE2135;
OS   Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC
OS   14298).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosomonas.
OX   NCBI_TaxID=228410;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298;
RX   PubMed=12700255; DOI=10.1128/jb.185.9.2759-2773.2003;
RA   Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L.,
RA   Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A.,
RA   Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.;
RT   "Complete genome sequence of the ammonia-oxidizing bacterium and obligate
RT   chemolithoautotroph Nitrosomonas europaea.";
RL   J. Bacteriol. 185:2759-2773(2003).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; AL954747; CAD86046.1; -; Genomic_DNA.
DR   RefSeq; WP_011112635.1; NC_004757.1.
DR   AlphaFoldDB; Q82T07; -.
DR   SMR; Q82T07; -.
DR   STRING; 228410.NE2135; -.
DR   DNASU; 1083097; -.
DR   EnsemblBacteria; CAD86046; CAD86046; NE2135.
DR   KEGG; neu:NE2135; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_4; -.
DR   OMA; LSTMDHC; -.
DR   OrthoDB; 45239at2; -.
DR   PhylomeDB; Q82T07; -.
DR   Proteomes; UP000001416; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..790
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_0000193882"
SQ   SEQUENCE   790 AA;  89642 MW;  3029FC9538C9DD5F CRC64;
     MTQLPQPLTP DELQKIDAYW RAANYLSVGQ IYLLDNPLLQ TPLTLQHIKP RLLGHWGTTP
     GLNFIYAHLN RIIRRDDLNM IYIAGPGHGG PALVANTYLE GTYSEHYPDI SQDIQGMKHL
     FRQFSFPGGI GSHATPEIPG SIHEGGELGY ALSHAFGAVF DNPDLIAACV VGDGEAETGP
     LATAWHSNKF LNPVHDGAVL PILHLNGYKI ANPTILARIS REELDQLFQG YGYQPYIVEG
     EDPLTMHQLM AGTLDQVLAE IRSIQTRARL DGVTQYPRWP MIILRTPKGW TGPATVDGLK
     TEGSWRSHQV PLSELAKKPE HIQQLEAWLR SYRPEELFDT QGRLVEPLQT LAPLGNRRMG
     ANPHANGGSL MKQLRMPDFR KYAVEIVQPG QIEAESTRIM GSFLRDIMCL NLKTCNFRVF
     GPDETASNRL GSLYDVTPKT WLAETLPEDE HLAPDGRVME ILSEHTCQGW LEGYLLTGRH
     GLFSCYEAFI HIVDSMFNQH AKWLKVSKEI PWRRPIASLN YLLTSHVWRQ DHNGFSHQDP
     GFIDHVINKK ADTIRIYLPP DANCLLYITD KCLRSRNFVN VIVAGKQPQL QWLDMDAAIK
     HCTAGIGIWG WASNDQAGEP DVVIACAGDV PTIEVLAAVS ILREHLPDLR IRVINVVDLM
     TLQHDREHPQ GLSDREFDTL FTTDKPIIFA YHGYPWLIHR LTYRRTNHAN LHVRGYKEEG
     TTTTPFDMTV LNDMDRFHLV DDVIDRVPHL GYKAAYLRQI MRDKLVEHRE YINRHGEDMP
     EIRDWKWTAP