ID   PHK_NITMU               Reviewed;         807 AA.
AC   Q2YAC5;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=Nmul_A0993;
OS   Nitrosospira multiformis (strain ATCC 25196 / NCIMB 11849 / C 71).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Nitrosomonadaceae; Nitrosospira.
OX   NCBI_TaxID=323848;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25196 / NCIMB 11849 / C 71;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M.,
RA   Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Lykidis A., Richardson P.;
RT   "Complete sequence of chromosome 1 of Nitrosospira multiformis ATCC
RT   25196.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000103; ABB74296.1; -; Genomic_DNA.
DR   RefSeq; WP_011380341.1; NZ_FNVK01000002.1.
DR   AlphaFoldDB; Q2YAC5; -.
DR   SMR; Q2YAC5; -.
DR   STRING; 323848.Nmul_A0993; -.
DR   EnsemblBacteria; ABB74296; ABB74296; Nmul_A0993.
DR   KEGG; nmu:Nmul_A0993; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_4; -.
DR   OMA; LSTMDHC; -.
DR   OrthoDB; 45239at2; -.
DR   Proteomes; UP000002718; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..807
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_1000068389"
SQ   SEQUENCE   807 AA;  91223 MW;  0B21C9A5E8F599BF CRC64;
     MNRASPAVKT ESNPLSTDEL RKIDAYWRAA NYLSVGQIYL LDNPLLKEPL TVTHIKPRLL
     GHWGTCPGLS FIYAHLNRII KKFDLDMFYV CGPGHGGPAM VANTWLEGSY SEFYPRISRD
     ATGMKRLFRQ FSFPGGIPSH VAPETAGSIN EGGELGYSLS HAFGAAFDNP DLIVACVVGD
     GEAETGPLAA SWHSNKFLNP ARDGAVLPIL HLNGYKIANP TILARISHEE LESLFAGYGY
     QPYFVEGSDP GPMHQSMAAV LDTAIESIRR IQREARSRGV NSGERQEAVT YPRWPLIILR
     SPKGWTGPEE VDGKKLEDYW RSHQVPLAEL GSKPDHLKQL EDWMRSYKPE ELFDENGCLM
     PELAALAPEG DRRMGANPHA NGGLLLKELE MPDFRSYAVD VPVPGTEVRE ATRETGKFLR
     DIMKLNLDSS NFRVMGPDET SSNRLDALFD VTARAWVAQQ LPEDEHLSPD GRVMEILSEH
     ICQGWLEGYL LTGRHGLFSC YEAFIHIVDS MFNQHAKWLK VSKEIPWRRP IASLNYLLTS
     HVWRQDHNGF SHQDPGFIDL VVNKKASIIR VYLPPDANTL LYITDKCLRS RNFINVIVAG
     KQPALQWLDM DAAIRHGSAG IGIWGWASND QEDEPDVVMA CAGDIPTLET LAAVDLLRRH
     VPELRIRVVN IVDLMTLQPR SEHPDGLSDW DFDTLFTTNK PIIFAYHGYP WLIHRLTYRR
     TNHPNLHVRG YKEEGTTTTP FDMTVLNDLD RFHLVMDVAD RVPKLSSKGA YLKQLMRDKL
     IDHKRYIRQY GEDMPEIRDW HWPSPGS