ID   PHK_PARUW               Reviewed;         798 AA.
AC   Q6MFC0;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=pc0005;
OS   Protochlamydia amoebophila (strain UWE25).
OC   Bacteria; Chlamydiae; Parachlamydiales; Parachlamydiaceae;
OC   Candidatus Protochlamydia.
OX   NCBI_TaxID=264201;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UWE25;
RX   PubMed=15073324; DOI=10.1126/science.1096330;
RA   Horn M., Collingro A., Schmitz-Esser S., Beier C.L., Purkhold U.,
RA   Fartmann B., Brandt P., Nyakatura G.J., Droege M., Frishman D., Rattei T.,
RA   Mewes H.-W., Wagner M.;
RT   "Illuminating the evolutionary history of chlamydiae.";
RL   Science 304:728-730(2004).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; BX908798; CAF22729.1; -; Genomic_DNA.
DR   RefSeq; WP_011174555.1; NC_005861.1.
DR   AlphaFoldDB; Q6MFC0; -.
DR   SMR; Q6MFC0; -.
DR   STRING; 264201.pc0005; -.
DR   EnsemblBacteria; CAF22729; CAF22729; PC_RS00020.
DR   KEGG; pcu:PC_RS00020; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_0; -.
DR   OMA; LSTMDHC; -.
DR   OrthoDB; 45239at2; -.
DR   Proteomes; UP000000529; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..798
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_0000193884"
SQ   SEQUENCE   798 AA;  90338 MW;  AB1C6A68E60E588E CRC64;
     MITKLPPTSE SNNSLSDELL EKINAYWRAA NYLSVGQIYL LDNPLLKKPL SIKDIKPRLL
     GHWGTTPGLN FIYVHLNRII KKFDLDMIYL IGPGHGGPGI VANTYLEGTY SEYYPHISQD
     AEGMQKLFKQ FSFPGGIPSH VAPETPGSIN EGGELGYSLS HAFGAAFNNP DLIVGCVIGD
     GEAETGPLAT AWHSNKFLNP AIDGAVLPIL HLNGYKIANP TILARISQEE LKSLFVGYGY
     KPYFVEGSDP QLMHRLMAET LDMIIKEIQE IQTNARKNGI VKRPIWPMII LRTPKGWTGP
     KEVDGKKTEN YWRSHQVPFS DMKEEHIKLL EEWLKSYRPE ELFDETGKLF PILAELAPKG
     KRRMGDNFHA NGGLLRKNLR LPDFRSYQLE VVTPGVVEAE STRIMGSFLR DVLKLNPHNF
     LVTGPDETAS NRLTNLFEVT QRRWLAEYLP EDTDGGNLSL EGRVLEILSE HTCLGWLEGY
     ILTGRHGFFS TYEAFAHIID SMFNQHAKWL QTTLTIPWRA PIPSINILLS SHVWRQDHNG
     FSHQDPGFID LVMNKKAAVV RVYLPPDSNT LLSVTDHCLR SLNYINVIVA GKQPALQYLS
     MEAAIKHCTA GIGIWEWASN DKGGEPDVVL ACAGDIPTLE ILAAVDILRQ SIPTLKIRVI
     NVVDLMTLQP KEEHPHGLSN TDFDEMFTTN KPIIFAYHGY PWLIHRLTYR RSNHSNIHVR
     GYKEEGTTTT PFDMVVLNEV DRFHLVGDVI DRVPKLGYLA AYTKQEMRHK LIEHKEYIHQ
     FGEDMPSVKN WKWPYGKE