ID   PHK_PEDPA               Reviewed;         787 AA.
AC   Q03H73;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=PEPE_0353;
OS   Pediococcus pentosaceus (strain ATCC 25745 / CCUG 21536 / LMG 10740 /
OS   183-1w).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC   Pediococcus.
OX   NCBI_TaxID=278197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25745 / CCUG 21536 / LMG 10740 / 183-1w;
RX   PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA   Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V.,
RA   Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V.,
RA   Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M.,
RA   Hawkins T., Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A.,
RA   Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W.,
RA   Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y.,
RA   Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R.,
RA   O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T.,
RA   Richardson P., Kozyavkin S., Weimer B.C., Mills D.A.;
RT   "Comparative genomics of the lactic acid bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; CP000422; ABJ67449.1; -; Genomic_DNA.
DR   RefSeq; WP_002832791.1; NC_008525.1.
DR   AlphaFoldDB; Q03H73; -.
DR   SMR; Q03H73; -.
DR   STRING; 278197.PEPE_0353; -.
DR   PRIDE; Q03H73; -.
DR   EnsemblBacteria; ABJ67449; ABJ67449; PEPE_0353.
DR   GeneID; 33062097; -.
DR   KEGG; ppe:PEPE_0353; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_9; -.
DR   OMA; LSTMDHC; -.
DR   OrthoDB; 45239at2; -.
DR   Proteomes; UP000000773; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..787
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_1000087372"
SQ   SEQUENCE   787 AA;  89724 MW;  8B7652ED5882A47C CRC64;
     MTDYSSKEYF DKLEKFWRAA NYLSVGQLYL KDNPLLKRDI KPEDVKVHPI GHWGTIPGQN
     YIYAHLNRVI NKYGVNMFYV EGPGHGGQVM VSNSYLDGSY TEAYPAITQD EEGMKKLFKQ
     FSWPGGVASH AAPVTPGSIH EGGELGYSLS HGVGAILDNP DQIAAVVVGD GEAETGPLAA
     SWQHNRFINP ITDGAVLPIL DINGYKLSNP SLTSRMSDEE LTEFFHGQHW DPYFVEGDDS
     EAMDPKMAEV MDKAIEKIQE IQKNARENHD ETMPYWPVIV FRSPKGWTGP KTWDNKVIEG
     TFRAHQIPIP VDQKNLEHVD ALIDWMKSYK PEELFDENGR VLPEIAEIAP KGEKRMASNP
     ITNGGVNPTD LNLPDYRDYA VDTTKRGQNI KQDMLVWSDY LRDVITKNPT NFRMFGPDET
     MSNRLYGLFE VTNRQFVAPI KKDWDEALAP EGRILDAQLS EHSAEGWLET YTLTGRHGIF
     TSYEAFLRVV DSMITQHFKW LRKADELDWR NDYPSLNLVS TSTSFQQDHN GYTHQDPGLL
     THLAEKKPEF IREYLPADAN SLLAISPLVM NDRNKINLII ASKQPRPQFY SMEEAEVLAK
     NGLGIIDWAS TTNGEEPDVV FAAAGTEPNM ESLAAINILH DNFPDLKIRF INVVDLLKLQ
     SPKVNPNGLS DEEFDRYFTK DKPVIFTFHG FEDLIRSIFF DRHNHNLHVH GYREEGDITT
     PFDMRVLNEL DRFHLAQDTI NSIPEFAEKG ADFSQQMDNT LERHYQYIRD NGDDLPEVTN
     WTWKDVN