ID   PHK_STRAW               Reviewed;         793 AA.
AC   Q82NM9;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Probable phosphoketolase {ECO:0000255|HAMAP-Rule:MF_01403};
DE            EC=4.1.2.- {ECO:0000255|HAMAP-Rule:MF_01403};
GN   OrderedLocusNames=SAV_1273;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01403};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000255|HAMAP-
CC       Rule:MF_01403}.
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DR   EMBL; BA000030; BAC68983.1; -; Genomic_DNA.
DR   RefSeq; WP_010982711.1; NZ_JZJK01000078.1.
DR   AlphaFoldDB; Q82NM9; -.
DR   SMR; Q82NM9; -.
DR   STRING; 227882.SAV_1273; -.
DR   EnsemblBacteria; BAC68983; BAC68983; SAVERM_1273.
DR   KEGG; sma:SAVERM_1273; -.
DR   eggNOG; COG3957; Bacteria.
DR   HOGENOM; CLU_013954_2_0_11; -.
DR   OMA; LSTMDHC; -.
DR   OrthoDB; 45239at2; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..793
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_0000193890"
SQ   SEQUENCE   793 AA;  88062 MW;  39D02CF9AF57E783 CRC64;
     MPQVEHQNST VLTDDELRTL DAHWRAANYL AAGQIYLLAN ALLTEPLSPA HIKPRLLGHW
     GTSPGLNLVH THLNRVIKAR DLDALCVWGP GHGGPAVLAN SWLEGSYSET YPDISRDAAG
     MGKLFRQFSF PGGVPSHVAP ETPGSIHEGG ELGYSLAHAY GAAFDNPDLL VACVIGDGEA
     ETGPLAASWH SNKFLDPVHD GAVLPILHLN GYKIANPTVL SRIPEPELDE LLRGYGHEPL
     HVTGDDPHQV HRALAEAFDR ALDRVALMQR TAREEGATER IRWPMIVLRT PKGWTGPAEV
     DGRPVEGTWR AHQVPLPEVR ENPEHLRQLE GWLRSYRPEE LFDADGRPTA DVLACVPHGA
     RRLGATPHAN GGLLLRPLPI PPLDRFAVAV DKPGATLHEP TRVLGDLLEQ VMKDTSARRD
     FRLVGPDETA SNRLDAVFDA SGKAWQAQTL PVDEHLDRHG RVMEILSEHT CQGWLEGYLL
     TGRHGLFSCY EAFVHIVDSM VNQHIKWLKT SRELAWRAPI ASLNYLLTSH VWRQDHNGFS
     HQDPGFVDHV LNKSPEAVRV YLPPDANTLL SVADHVLRSR DYVNVVVAGK QPCFDWLSME
     QARAHCARGA GIWEWAGTQN DGEPDVVLAC AGDVPTQEVL AASALLRRHL PALAVRVVNV
     VDMTRLLPRE AHPHGMSDFE YDGLFTTDKP VIFAYHGYPW LIHRLAYSRT GHGNLHVRGY
     KEMGTTTTPF DMVVRNDLDR YRLVMDVVDR VPGLGVRAAA VRQTMADART RHHAWIREHG
     TDLPEVANWT WEA