ID   PHK_SYNY3               Reviewed;         805 AA.
AC   P74690;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2005, sequence version 2.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Probable phosphoketolase;
DE            EC=4.1.2.-;
GN   OrderedLocusNames=slr0453;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000305};
CC   -!- SIMILARITY: Belongs to the XFP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAA18808.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000022; BAA18808.1; ALT_INIT; Genomic_DNA.
DR   PIR; S76896; S76896.
DR   AlphaFoldDB; P74690; -.
DR   SMR; P74690; -.
DR   STRING; 1148.1653898; -.
DR   PaxDb; P74690; -.
DR   EnsemblBacteria; BAA18808; BAA18808; BAA18808.
DR   KEGG; syn:slr0453; -.
DR   eggNOG; COG3957; Bacteria.
DR   InParanoid; P74690; -.
DR   OMA; KQPRQQW; -.
DR   PhylomeDB; P74690; -.
DR   BRENDA; 4.1.2.9; 6192.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.920; -; 1.
DR   HAMAP; MF_01403; Phosphoketolase; 1.
DR   InterPro; IPR023962; Phosphoketolase.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005593; Xul5P/Fru6P_PKetolase.
DR   InterPro; IPR018969; Xul5P/Fru6P_PKetolase_C.
DR   InterPro; IPR019790; Xul5P/Fru6P_PKetolase_CS.
DR   InterPro; IPR018970; Xul5P/Fru6P_PKetolase_N.
DR   InterPro; IPR019789; Xul5P/Fru6P_PKetolase_ThDP_BS.
DR   PANTHER; PTHR31273; PTHR31273; 1.
DR   Pfam; PF03894; XFP; 1.
DR   Pfam; PF09363; XFP_C; 1.
DR   Pfam; PF09364; XFP_N; 1.
DR   PIRSF; PIRSF017245; Phosphoketolase; 1.
DR   SUPFAM; SSF52518; SSF52518; 2.
DR   PROSITE; PS60002; PHOSPHOKETOLASE_1; 1.
DR   PROSITE; PS60003; PHOSPHOKETOLASE_2; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Thiamine pyrophosphate.
FT   CHAIN           1..805
FT                   /note="Probable phosphoketolase"
FT                   /id="PRO_0000193894"
SQ   SEQUENCE   805 AA;  90879 MW;  B8C63C3FAB477484 CRC64;
     MVTSPFSLSP FGQARSTVTG NPLDPTELNQ MHGFWRAANY LAVGMIYLRD NPLLREPLQP
     EQIKHRLLGH WGSSPGISFL YTHLNRIIRK FDQDMLYMVG PGHGAPGFLG PCYLEGSYSR
     FFAECSEDED GMKRFFKQFS FPGGIGSHCT PETPGSIHEG GELGYCLSHA YGAAFDNPNL
     IVVGLAGDGE SETGPLATSW HSNKFINPIR DGAVLPVLHL NGYKINNPSV LSRISHEELK
     ALFEGYGYTP YFVEGSDPES MHQAMAATLD HCVSEIHQIQ QEARSTGIAV RPRWPMVVMR
     TPKGWTGPDY VDGHKVEGFW RSHQVPMGGM HENPAHLQQL EAWMRSYKPE ELFDEQGTLK
     PGFKAIAPEG DKRLGSTPYA NGGLLRRGLK MPDFRQYGID VDQPGTIEAP NTAPLGVFLR
     DVMANNMTNF RLFGPDENSS NKLHAVYEVS KKFWIAEYLE EDQDGGELSP DGRVMEMLSE
     HTLEGWLEAY LLTGRHGFFA TYESFAHVIT SMVNQHAKWL DICRHLNWRA DISSLNILMT
     STVWRQDHNG FTHQDPGFLD VILNKSPDVV RIYLPPDVNS LLSVADHCLQ SKNYINIIVC
     DKQAHLQYQD MTSAIRNCTK GVDIWEWASN DAGTEPDVVM AAAGDIPTKE ALAATAMLRQ
     FFPNLRIRFV SVIDLLKLQP ESEHPHGLSD RDFDSLFTTD KPIIFNFHAY PWLIHRLTYR
     RTNHGNLHVR GYKEKGNINT PMDLAIQNQI DRFSLAIDVI DRLPQLRVAG AHIKEMLKDM
     QIDCTNYAYE HGIDMPEIVN WRWPL