PHL11_ARATH
ID PHL11_ARATH Reviewed; 254 AA.
AC Q9SN26;
DT 09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Phytolongin Phyl1.1 {ECO:0000303|PubMed:19889231};
GN Name=PHYL1.1 {ECO:0000303|PubMed:19889231};
GN OrderedLocusNames=At4g10170 {ECO:0000312|Araport:AT4G10170};
GN ORFNames=F28M11.90 {ECO:0000312|EMBL:CAB39769.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, GENE FAMILY, NOMENCLATURE, AND 3D-STRUCTURE MODELING.
RX PubMed=19889231; DOI=10.1186/1471-2164-10-510;
RA Vedovato M., Rossi V., Dacks J.B., Filippini F.;
RT "Comparative analysis of plant genomes allows the definition of the
RT 'Phytolongins': a novel non-SNARE longin domain protein family.";
RL BMC Genomics 10:510-510(2009).
CC -!- FUNCTION: Non-SNARE longin protein involved in membrane-trafficking
CC machinery. {ECO:0000305|PubMed:19889231}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type IV
CC membrane protein {ECO:0000250|UniProtKB:Q12255}.
CC -!- SIMILARITY: Belongs to the synaptobrevin family. {ECO:0000305}.
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DR EMBL; AL049487; CAB39769.1; -; Genomic_DNA.
DR EMBL; AL161516; CAB78140.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82850.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE82851.1; -; Genomic_DNA.
DR EMBL; BT004609; AAO42855.1; -; mRNA.
DR EMBL; AK227497; BAE99497.1; -; mRNA.
DR PIR; T04067; T04067.
DR RefSeq; NP_192755.1; NM_117085.5.
DR RefSeq; NP_974527.1; NM_202798.2.
DR AlphaFoldDB; Q9SN26; -.
DR SMR; Q9SN26; -.
DR STRING; 3702.AT4G10170.1; -.
DR iPTMnet; Q9SN26; -.
DR PaxDb; Q9SN26; -.
DR PRIDE; Q9SN26; -.
DR ProteomicsDB; 236675; -.
DR EnsemblPlants; AT4G10170.1; AT4G10170.1; AT4G10170.
DR EnsemblPlants; AT4G10170.2; AT4G10170.2; AT4G10170.
DR GeneID; 826608; -.
DR Gramene; AT4G10170.1; AT4G10170.1; AT4G10170.
DR Gramene; AT4G10170.2; AT4G10170.2; AT4G10170.
DR KEGG; ath:AT4G10170; -.
DR Araport; AT4G10170; -.
DR TAIR; locus:2124705; AT4G10170.
DR eggNOG; ENOG502QQFW; Eukaryota.
DR HOGENOM; CLU_088757_0_0_1; -.
DR InParanoid; Q9SN26; -.
DR OMA; GIWLAIC; -.
DR OrthoDB; 1196118at2759; -.
DR PhylomeDB; Q9SN26; -.
DR PRO; PR:Q9SN26; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q9SN26; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd14824; Longin; 1.
DR InterPro; IPR011012; Longin-like_dom_sf.
DR InterPro; IPR010908; Longin_dom.
DR InterPro; IPR044783; PHYL.
DR PANTHER; PTHR47461; PTHR47461; 1.
DR SMART; SM01270; Longin; 1.
DR SUPFAM; SSF64356; SSF64356; 1.
DR PROSITE; PS50859; LONGIN; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Membrane; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..254
FT /note="Phytolongin Phyl1.1"
FT /id="PRO_0000434812"
FT TRANSMEM 226..246
FT /note="Helical; Anchor for type IV membrane protein"
FT /evidence="ECO:0000255"
FT DOMAIN 12..113
FT /note="Longin"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00231"
FT REGION 138..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 254 AA; 28361 MW; 332B577512B8008B CRC64;
MGLIKNTVHY CCVSRDNQIL YSYNGGDQTN ESLAALCLEK SPPFHTWYFE TIGKRRFGFL
IGDGFVYFAI VDEVLKRSSV LKFLEHLRDE FKKAARENSR GSFTAMIGSI NVEDQLVPVV
TRLIASLERV AESSSNNELK SSNLGEQSEG SNSTKAPLLG RLSKQEKKKG KDHVIELEEH
RKSNDRGNIT DDSAGAGTSL EKECVSSSGR SVTQSFEWKW RRLVQIVLAI DAAICLTLFG
IWLAICRGIE CTRS
