PHL6_ARATH
ID PHL6_ARATH Reviewed; 449 AA.
AC Q949U2; Q8LFN4; Q9LSH8;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 25-MAY-2022, entry version 150.
DE RecName: Full=Myb family transcription factor PHL6 {ECO:0000305};
DE AltName: Full=Protein PHR1-LIKE 6 {ECO:0000305};
GN Name=PHL6 {ECO:0000305};
GN OrderedLocusNames=At3g13040 {ECO:0000312|Araport:AT3G13040};
GN ORFNames=MGH6.22 {ECO:0000312|EMBL:BAB02514.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAK92826.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=11511543; DOI=10.1101/gad.204401;
RA Rubio V., Linhares F., Solano R., Martin A.C., Iglesias J., Leyva A.,
RA Paz-Ares J.;
RT "A conserved MYB transcription factor involved in phosphate starvation
RT signaling both in vascular plants and in unicellular algae.";
RL Genes Dev. 15:2122-2133(2001).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- SIMILARITY: Belongs to the MYB-CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAM61311.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB02514.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB026645; BAB02514.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75281.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75282.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM65836.1; -; Genomic_DNA.
DR EMBL; AY050889; AAK92826.1; -; mRNA.
DR EMBL; AY096674; AAM20308.1; -; mRNA.
DR EMBL; AY084738; AAM61311.1; ALT_INIT; mRNA.
DR RefSeq; NP_001319536.1; NM_001338022.1.
DR RefSeq; NP_566442.1; NM_112141.3.
DR RefSeq; NP_974298.1; NM_202569.1.
DR AlphaFoldDB; Q949U2; -.
DR SMR; Q949U2; -.
DR IntAct; Q949U2; 1.
DR STRING; 3702.AT3G13040.1; -.
DR iPTMnet; Q949U2; -.
DR PaxDb; Q949U2; -.
DR PRIDE; Q949U2; -.
DR ProteomicsDB; 236349; -.
DR EnsemblPlants; AT3G13040.1; AT3G13040.1; AT3G13040.
DR EnsemblPlants; AT3G13040.2; AT3G13040.2; AT3G13040.
DR EnsemblPlants; AT3G13040.3; AT3G13040.3; AT3G13040.
DR GeneID; 820490; -.
DR Gramene; AT3G13040.1; AT3G13040.1; AT3G13040.
DR Gramene; AT3G13040.2; AT3G13040.2; AT3G13040.
DR Gramene; AT3G13040.3; AT3G13040.3; AT3G13040.
DR KEGG; ath:AT3G13040; -.
DR Araport; AT3G13040; -.
DR TAIR; locus:2089260; AT3G13040.
DR eggNOG; ENOG502QSXE; Eukaryota.
DR HOGENOM; CLU_045049_0_0_1; -.
DR InParanoid; Q949U2; -.
DR OMA; MAHTCTA; -.
DR OrthoDB; 929612at2759; -.
DR PRO; PR:Q949U2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q949U2; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR025756; Myb_CC_LHEQLE.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR044848; PHR1-like.
DR PANTHER; PTHR31314; PTHR31314; 1.
DR Pfam; PF14379; Myb_CC_LHEQLE; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..449
FT /note="Myb family transcription factor PHL6"
FT /id="PRO_0000436863"
FT DOMAIN 238..298
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 269..294
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 49..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 301..327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 334..354
FT /note="Coiled coil"
FT /evidence="ECO:0000305"
FT REGION 376..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 347..352
FT /note="LHEQLE"
FT /evidence="ECO:0000305"
FT COMPBIAS 378..417
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..449
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 351
FT /note="L -> Q (in Ref. 4; AAM61311)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 449 AA; 50112 MW; 3D7186C60B489138 CRC64;
MYIKAIMNRH RLLSAATDEC NKKLGQACSS SLSPVHNFLN VQPEHRKTPF IRSQSPDSPG
QLWPKNSSQS TFSRSSTFCT NLYLSSSSTS ETQKHLGNSL PFLPDPSSYT HSASGVESAR
SPSIFTEDLG NQCDGGNSGS LLKDFLNLSG DACSDGDFHD FGCSNDSYCL SDQMELQFLS
DELELAITDR AETPRLDEIY ETPLASNPVT RLSPSQSCVP GAMSVDVVSS HPSPGSAANQ
KSRMRWTPEL HESFVKAVIK LEGPEKATPK AVKKLMNVEG LTIYHVKSHL QKYRLAKYMP
EKKEEKRTDN SEEKKLALSK SEADEKKKGA IQLTEALRMQ MEVQKQLHEQ LEVQRVLQLR
IEEHAKYLEK MLEEQRKTGR WISSSSQTVL SPSDDSIPDS QNMSKTKASS PQPPLPAENK
ASETEDDKCE SPQKRRRLEN IAESEDPKR
