PHL7_ARATH
ID PHL7_ARATH Reviewed; 286 AA.
AC Q9SJW0; F4IM72;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 156.
DE RecName: Full=Myb family transcription factor PHL7 {ECO:0000305};
DE AltName: Full=Protein PHR1-LIKE 7 {ECO:0000305};
GN Name=PHL7 {ECO:0000305};
GN OrderedLocusNames=At2g01060 {ECO:0000312|Araport:AT2G01060};
GN ORFNames=F23H14.3 {ECO:0000312|EMBL:AAF18654.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RX PubMed=11511543; DOI=10.1101/gad.204401;
RA Rubio V., Linhares F., Solano R., Martin A.C., Iglesias J., Leyva A.,
RA Paz-Ares J.;
RT "A conserved MYB transcription factor involved in phosphate starvation
RT signaling both in vascular plants and in unicellular algae.";
RL Genes Dev. 15:2122-2133(2001).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9SJW0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9SJW0-2; Sequence=VSP_058433;
CC -!- SIMILARITY: Belongs to the MYB-CC family. {ECO:0000305}.
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DR EMBL; AC006837; AAF18654.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05392.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC05393.1; -; Genomic_DNA.
DR EMBL; AF370550; AAK48977.1; -; mRNA.
DR EMBL; BT000013; AAN15332.1; -; mRNA.
DR EMBL; AY084725; AAM61299.1; -; mRNA.
DR PIR; B84420; B84420.
DR RefSeq; NP_178216.1; NM_126168.5. [Q9SJW0-1]
DR RefSeq; NP_973385.1; NM_201656.2. [Q9SJW0-2]
DR AlphaFoldDB; Q9SJW0; -.
DR SMR; Q9SJW0; -.
DR IntAct; Q9SJW0; 4.
DR STRING; 3702.AT2G01060.1; -.
DR PaxDb; Q9SJW0; -.
DR PRIDE; Q9SJW0; -.
DR ProteomicsDB; 236748; -. [Q9SJW0-1]
DR EnsemblPlants; AT2G01060.1; AT2G01060.1; AT2G01060. [Q9SJW0-1]
DR EnsemblPlants; AT2G01060.2; AT2G01060.2; AT2G01060. [Q9SJW0-2]
DR GeneID; 814630; -.
DR Gramene; AT2G01060.1; AT2G01060.1; AT2G01060. [Q9SJW0-1]
DR Gramene; AT2G01060.2; AT2G01060.2; AT2G01060. [Q9SJW0-2]
DR KEGG; ath:AT2G01060; -.
DR Araport; AT2G01060; -.
DR TAIR; locus:2045761; AT2G01060.
DR eggNOG; ENOG502QU84; Eukaryota.
DR HOGENOM; CLU_053944_0_0_1; -.
DR InParanoid; Q9SJW0; -.
DR OMA; CAVPYYS; -.
DR PhylomeDB; Q9SJW0; -.
DR PRO; PR:Q9SJW0; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SJW0; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR025756; Myb_CC_LHEQLE.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR044848; PHR1-like.
DR PANTHER; PTHR31314; PTHR31314; 1.
DR Pfam; PF14379; Myb_CC_LHEQLE; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; DNA-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..286
FT /note="Myb family transcription factor PHL7"
FT /id="PRO_0000436864"
FT DOMAIN 12..72
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 43..68
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 74..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 152..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 104..124
FT /evidence="ECO:0000255"
FT MOTIF 117..122
FT /note="LHEQLE"
FT /evidence="ECO:0000305"
FT COMPBIAS 75..91
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..214
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..49
FT /note="Missing (in isoform 2)"
FT /id="VSP_058433"
SQ SEQUENCE 286 AA; 31075 MW; A33D375EBB5DB15D CRC64;
MEADNGGPNS SHASKQRLRW THELHERFVD AVAQLGGPDR ATPKGVLRVM GVQGLTIYHV
KSHLQKYRLA KYLPDSSSEG KKTDKKESGD MLSGLDGSSG MQITEALKLQ MEVQKRLHEQ
LEVQRQLQLR IEAQGKYLKK IIEEQQRLSG VLGEPSAPVT GDSDPATPAP TSESPLQDKS
GKDCGPDKSL SVDESLSSYR EPLTPDSGCN IGSPDESTGE ERLSKKPRLV RGAAGYTPDI
VVGHPILESG LNTSYHQSDH VLAFDQPSTS LLGAEEQLDK VSGDNL
