PHL8_ARATH
ID PHL8_ARATH Reviewed; 336 AA.
AC F4I274; A8MSE5; Q9SEZ2;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Myb family transcription factor PHL8 {ECO:0000305};
DE AltName: Full=Protein PHR1-LIKE 8 {ECO:0000305};
GN Name=PHL8 {ECO:0000305};
GN OrderedLocusNames=At1g69580 {ECO:0000312|Araport:AT1G69580};
GN ORFNames=F24J1.30 {ECO:0000312|EMBL:AAF24605.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 5-336 (ISOFORM 1).
RA Bautista V.R., Kim C.J., Chen H., Quinitio C., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=11511543; DOI=10.1101/gad.204401;
RA Rubio V., Linhares F., Solano R., Martin A.C., Iglesias J., Leyva A.,
RA Paz-Ares J.;
RT "A conserved MYB transcription factor involved in phosphate starvation
RT signaling both in vascular plants and in unicellular algae.";
RL Genes Dev. 15:2122-2133(2001).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=F4I274-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4I274-2; Sequence=VSP_058434;
CC -!- SIMILARITY: Belongs to the MYB-CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF24605.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC021046; AAF24605.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE34951.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34952.1; -; Genomic_DNA.
DR EMBL; BT029516; ABL66772.1; -; mRNA.
DR PIR; E96717; E96717.
DR RefSeq; NP_001077798.1; NM_001084329.1. [F4I274-2]
DR RefSeq; NP_177117.2; NM_105627.3. [F4I274-1]
DR AlphaFoldDB; F4I274; -.
DR SMR; F4I274; -.
DR STRING; 3702.AT1G69580.2; -.
DR PRIDE; F4I274; -.
DR ProteomicsDB; 235057; -. [F4I274-1]
DR EnsemblPlants; AT1G69580.1; AT1G69580.1; AT1G69580. [F4I274-1]
DR EnsemblPlants; AT1G69580.2; AT1G69580.2; AT1G69580. [F4I274-2]
DR GeneID; 843294; -.
DR Gramene; AT1G69580.1; AT1G69580.1; AT1G69580. [F4I274-1]
DR Gramene; AT1G69580.2; AT1G69580.2; AT1G69580. [F4I274-2]
DR KEGG; ath:AT1G69580; -.
DR Araport; AT1G69580; -.
DR TAIR; locus:2026739; AT1G69580.
DR eggNOG; ENOG502QT5C; Eukaryota.
DR HOGENOM; CLU_053944_3_2_1; -.
DR OMA; NICGDEQ; -.
DR OrthoDB; 880893at2759; -.
DR PRO; PR:F4I274; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I274; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR025756; Myb_CC_LHEQLE.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR044848; PHR1-like.
DR PANTHER; PTHR31499; PTHR31499; 1.
DR Pfam; PF14379; Myb_CC_LHEQLE; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; DNA-binding; Homeobox; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..336
FT /note="Myb family transcription factor PHL8"
FT /id="PRO_0000436865"
FT DOMAIN 31..91
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 62..87
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 100..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 139..159
FT /evidence="ECO:0000255"
FT MOTIF 152..157
FT /note="LHEQLE"
FT /evidence="ECO:0000305"
FT VAR_SEQ 134
FT /note="E -> DR (in isoform 2)"
FT /id="VSP_058434"
SQ SEQUENCE 336 AA; 37896 MW; 4A6CBABCD5025A80 CRC64;
MCLLMEINNN ANNTNTTIDN HKAKMSLVLS TDAKPRLKWT CDLHHKFIEA VNQLGGPNKA
TPKGLMKVME IPGLTLYHLK SHLQKYRLGK SMKFDDNKLE VSSASENQEV ESKNDSRDLR
GCSVTEENSN PAKEGLQITE ALQMQMEVQK KLHEQIEVQR HLQVKIEAQG KYLQSVLMKA
QQTLAGYSSS NLGMDFARTE LSRLASMVNR GCPSTSFSEL TQVEEEEEGF LWYKKPENRG
ISQLRCSVES SLTSSETSET KLDTDNNLNK SIELPLMEIN SEVMKGKKRS INDVVCVEQP
LMKRAFGVDD DEHLKLSLNT YKKDMEACTN IGLGFN
