PHLC_ARATH
ID PHLC_ARATH Reviewed; 235 AA.
AC Q8VYI2; Q9LTW1;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 149.
DE RecName: Full=Myb family transcription factor PHL12 {ECO:0000305};
DE AltName: Full=Protein PHR1-LIKE 12 {ECO:0000305};
GN Name=PHL12 {ECO:0000305};
GN OrderedLocusNames=At3g12730 {ECO:0000312|Araport:AT3G12730};
GN ORFNames=MBK21.9 {ECO:0000312|EMBL:BAB02417.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|EMBL:AAL50101.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:131-135(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY.
RX PubMed=11511543; DOI=10.1101/gad.204401;
RA Rubio V., Linhares F., Solano R., Martin A.C., Iglesias J., Leyva A.,
RA Paz-Ares J.;
RT "A conserved MYB transcription factor involved in phosphate starvation
RT signaling both in vascular plants and in unicellular algae.";
RL Genes Dev. 15:2122-2133(2001).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=15923329; DOI=10.1104/pp.105.060202;
RA Zhao C., Craig J.C., Petzold H.E., Dickerman A.W., Beers E.P.;
RT "The xylem and phloem transcriptomes from secondary tissues of the
RT Arabidopsis root-hypocotyl.";
RL Plant Physiol. 138:803-818(2005).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- TISSUE SPECIFICITY: Expressed in phloem and/or cambium.
CC {ECO:0000269|PubMed:15923329}.
CC -!- SIMILARITY: Belongs to the MYB-CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02417.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB024033; BAB02417.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75240.1; -; Genomic_DNA.
DR EMBL; AY070764; AAL50101.1; -; mRNA.
DR EMBL; AY143916; AAN28855.1; -; mRNA.
DR RefSeq; NP_187879.2; NM_112109.4.
DR AlphaFoldDB; Q8VYI2; -.
DR SMR; Q8VYI2; -.
DR STRING; 3702.AT3G12730.1; -.
DR PaxDb; Q8VYI2; -.
DR PRIDE; Q8VYI2; -.
DR ProteomicsDB; 234999; -.
DR EnsemblPlants; AT3G12730.1; AT3G12730.1; AT3G12730.
DR GeneID; 820455; -.
DR Gramene; AT3G12730.1; AT3G12730.1; AT3G12730.
DR KEGG; ath:AT3G12730; -.
DR Araport; AT3G12730; -.
DR TAIR; locus:2087740; AT3G12730.
DR eggNOG; ENOG502QQUN; Eukaryota.
DR HOGENOM; CLU_1442964_0_0_1; -.
DR InParanoid; Q8VYI2; -.
DR OMA; IRMDAHQ; -.
DR OrthoDB; 1126159at2759; -.
DR PhylomeDB; Q8VYI2; -.
DR PRO; PR:Q8VYI2; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q8VYI2; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR025756; Myb_CC_LHEQLE.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR044848; PHR1-like.
DR PANTHER; PTHR31499; PTHR31499; 1.
DR Pfam; PF14379; Myb_CC_LHEQLE; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; DNA-binding; Nucleus; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..235
FT /note="Myb family transcription factor PHL12"
FT /id="PRO_0000436869"
FT DOMAIN 20..80
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 51..76
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..139
FT /note="Coiled coil"
FT /evidence="ECO:0000305"
SQ SEQUENCE 235 AA; 26929 MW; 4C157174A7B7282D CRC64;
MMQSREEIRD DSSSGLVLTT DPKPRLRWTT ELHERFVDAV THLGGPEKAT PKTIMRVMGV
KGLTLYHLKS HLQKFRLGKQ PHKEHSQNHS ICIRDTNRAS MLDLRRNAVF TTSPLIIGRN
MNEMQMEVQR RIEEEVVIER QVNQRIAAQG KYMESMLEKA CETQEASLTK DYSTLFFDRT
NICNNTSSIP IPWFEDHFPS SSSMDSTLIL PDINSNFSLQ DSRSSITKGR TVCLG
