PHLD_ARATH
ID PHLD_ARATH Reviewed; 442 AA.
AC F4J3P7; Q8GWU5; Q9M842;
DT 06-JUL-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Myb family transcription factor PHL13 {ECO:0000305};
DE AltName: Full=Protein PHR1-LIKE 13 {ECO:0000305};
GN Name=PHL13 {ECO:0000305};
GN OrderedLocusNames=At3g04450 {ECO:0000312|Araport:AT3G04450};
GN ORFNames=T27C4.10 {ECO:0000312|EMBL:BAC43227.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY.
RX PubMed=11511543; DOI=10.1101/gad.204401;
RA Rubio V., Linhares F., Solano R., Martin A.C., Iglesias J., Leyva A.,
RA Paz-Ares J.;
RT "A conserved MYB transcription factor involved in phosphate starvation
RT signaling both in vascular plants and in unicellular algae.";
RL Genes Dev. 15:2122-2133(2001).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=F4J3P7-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4J3P7-2; Sequence=VSP_058440;
CC -!- SIMILARITY: Belongs to the MYB-CC family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF63776.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC022287; AAF63776.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE74083.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74084.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64795.1; -; Genomic_DNA.
DR EMBL; AK118630; BAC43227.1; -; mRNA.
DR EMBL; BT005352; AAO63416.1; -; mRNA.
DR RefSeq; NP_001189806.1; NM_001202877.2. [F4J3P7-2]
DR RefSeq; NP_001319469.1; NM_001337525.1. [F4J3P7-1]
DR RefSeq; NP_001326800.1; NM_001337527.1. [F4J3P7-2]
DR AlphaFoldDB; F4J3P7; -.
DR SMR; F4J3P7; -.
DR STRING; 3702.AT3G04450.1; -.
DR PaxDb; F4J3P7; -.
DR PRIDE; F4J3P7; -.
DR ProteomicsDB; 236348; -. [F4J3P7-1]
DR EnsemblPlants; AT3G04450.1; AT3G04450.1; AT3G04450. [F4J3P7-1]
DR EnsemblPlants; AT3G04450.2; AT3G04450.2; AT3G04450. [F4J3P7-2]
DR EnsemblPlants; AT3G04450.4; AT3G04450.4; AT3G04450. [F4J3P7-2]
DR GeneID; 819601; -.
DR Gramene; AT3G04450.1; AT3G04450.1; AT3G04450. [F4J3P7-1]
DR Gramene; AT3G04450.2; AT3G04450.2; AT3G04450. [F4J3P7-2]
DR Gramene; AT3G04450.4; AT3G04450.4; AT3G04450. [F4J3P7-2]
DR KEGG; ath:AT3G04450; -.
DR Araport; AT3G04450; -.
DR TAIR; locus:2100880; AT3G04450.
DR eggNOG; ENOG502RQ9X; Eukaryota.
DR InParanoid; F4J3P7; -.
DR OrthoDB; 812231at2759; -.
DR PRO; PR:F4J3P7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; F4J3P7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR025756; Myb_CC_LHEQLE.
DR InterPro; IPR017930; Myb_dom.
DR InterPro; IPR006447; Myb_dom_plants.
DR InterPro; IPR044848; PHR1-like.
DR PANTHER; PTHR31314; PTHR31314; 1.
DR Pfam; PF14379; Myb_CC_LHEQLE; 1.
DR Pfam; PF00249; Myb_DNA-binding; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
DR PROSITE; PS51294; HTH_MYB; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; DNA-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..442
FT /note="Myb family transcription factor PHL13"
FT /id="PRO_0000436870"
FT DOMAIN 235..295
FT /note="HTH myb-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT DNA_BIND 266..291
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00625"
FT REGION 329..349
FT /note="Coiled coil"
FT /evidence="ECO:0000305"
FT REGION 370..442
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 342..347
FT /note="LHEQLE"
FT /evidence="ECO:0000305"
FT COMPBIAS 377..433
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..40
FT /note="Missing (in isoform 2)"
FT /id="VSP_058440"
SQ SEQUENCE 442 AA; 49400 MW; B6A98032533F6091 CRC64;
MTLASDFGFP SAISSSFTIL EERYHNNFPN TLCVSSGQES MNNNPVPCQV FPLVSGGSSG
GNLFSSSSGF CNGVYVSSSS QARPSVSTVP RDRITVAHVS GEGQRQECPV ETHSLQLINQ
PQEQKIMTWS SDQIRGFFDF PVPDPQAASS RTMVSSKEVL SKCEWPDWAD QLISDDSLEP
NWSELLGDPN VLNLYSKIET QSSDIARQEI VFRNQHQVDP SMEPFNAKSP PASSMTSKQR
MRWTPELHEA FVEAINQLGG SERATPKAVL KLINSPGLTV YHVKSHLQKY RTARYKPELS
KDTEEPLVKN LKTIEDIKSL DLKTSIEITE ALRLQMKVQK QLHEQLEIQR SLQLQIEEQG
RYLQMMIEKQ QKMQENKKDS TSSSSMPEAD PSAPSPNLSQ PFLHKATNSE PSITQKLQNG
SSTMDQSEST SGTSNRKRVR ED
