ID   PHLP3_DICDI             Reviewed;         184 AA.
AC   Q71A37; Q54B66;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Phosducin-like protein 3;
GN   Name=phlp3; ORFNames=DDB_G0293848;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND THIOREDOXIN FOLD REGION.
RX   PubMed=14517243; DOI=10.1093/emboj/cdg508;
RA   Blaauw M., Knol J.C., Kortholt A., Roelofs J., Ruchira X., Postma M.,
RA   Visser A.J.W.G., van Haastert P.J.M.;
RT   "Phosducin-like proteins in Dictyostelium discoideum: implications for the
RT   phosducin family of proteins.";
RL   EMBO J. 22:5047-5057(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the phosducin family. {ECO:0000305}.
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DR   EMBL; AF540060; AAQ11194.1; -; mRNA.
DR   EMBL; AAFI02000223; EAL60495.1; -; Genomic_DNA.
DR   RefSeq; XP_628922.1; XM_628920.1.
DR   AlphaFoldDB; Q71A37; -.
DR   SMR; Q71A37; -.
DR   STRING; 44689.DDB0201655; -.
DR   PaxDb; Q71A37; -.
DR   PRIDE; Q71A37; -.
DR   EnsemblProtists; EAL60495; EAL60495; DDB_G0293848.
DR   GeneID; 8629464; -.
DR   KEGG; ddi:DDB_G0293848; -.
DR   dictyBase; DDB_G0293848; phlp3.
DR   eggNOG; KOG1672; Eukaryota.
DR   HOGENOM; CLU_072378_0_1_1; -.
DR   InParanoid; Q71A37; -.
DR   OMA; QVLPCVI; -.
DR   PhylomeDB; Q71A37; -.
DR   PRO; PR:Q71A37; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IEA:InterPro.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..184
FT                   /note="Phosducin-like protein 3"
FT                   /id="PRO_0000326489"
FT   REGION          45..184
FT                   /note="Thioredoxin fold"
SQ   SEQUENCE   184 AA;  21035 MW;  BA32A734977E4E89 CRC64;
     MSENNTNNGL DEDFDDDDEL AKIREQRMKQ LKEESKLKQS FLSTHGELKE IDEQDFLKEV
     TGTDNVVVHF YHSDFQRCKI LDKSLEILAK THLGTKFLKV NAEKAQFFTG KLGIRILPTL
     VFFSNGIAVD RCVGFEEFGG IDSFKIEQLA IRISKAGVLD FKHTTGLKII SKQDVKNNKF
     KEDD