ID   PHNC1_HALMA             Reviewed;         273 AA.
AC   Q5V6B8;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Phosphonates import ATP-binding protein PhnC 1;
DE            EC=7.3.2.2;
GN   Name=phnC1; OrderedLocusNames=pNG7233;
OS   Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM
OS   B-1809) (Halobacterium marismortui).
OG   Plasmid pNG700.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Haloarculaceae; Haloarcula.
OX   NCBI_TaxID=272569;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809;
RX   PubMed=15520287; DOI=10.1101/gr.2700304;
RA   Baliga N.S., Bonneau R., Facciotti M.T., Pan M., Glusman G., Deutsch E.W.,
RA   Shannon P., Chiu Y., Weng R.S., Gan R.R., Hung P., Date S.V., Marcotte E.,
RA   Hood L., Ng W.V.;
RT   "Genome sequence of Haloarcula marismortui: a halophilic archaeon from the
RT   Dead Sea.";
RL   Genome Res. 14:2221-2234(2004).
CC   -!- FUNCTION: Part of the ABC transporter complex PhnCDE involved in
CC       phosphonates import. Responsible for energy coupling to the transport
CC       system (By similarity). {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + phosphonate(out) = ADP + H(+) + phosphate +
CC         phosphonate(in); Xref=Rhea:RHEA:18065, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16215, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.2;
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PhnC),
CC       two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).
CC       {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Phosphonates
CC       importer (TC 3.A.1.9.1) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAV44934.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AY596296; AAV44934.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_049938565.1; NZ_CP039137.1.
DR   AlphaFoldDB; Q5V6B8; -.
DR   SMR; Q5V6B8; -.
DR   EnsemblBacteria; AAV44934; AAV44934; pNG7233.
DR   GeneID; 40151493; -.
DR   KEGG; hma:pNG7233; -.
DR   PATRIC; fig|272569.17.peg.663; -.
DR   HOGENOM; CLU_2190957_0_0_2; -.
DR   Proteomes; UP000001169; Plasmid pNG700.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015416; F:ABC-type phosphonate transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Phosphonate transport; Plasmid; Reference proteome; Translocase; Transport.
FT   CHAIN           1..273
FT                   /note="Phosphonates import ATP-binding protein PhnC 1"
FT                   /id="PRO_0000092741"
FT   DOMAIN          18..249
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         50..57
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   273 AA;  28970 MW;  11B43244002858F8 CRC64;
     MKSKYTARPE GKQSGQGLVF DSVTKRFGGK VAVRDVSLKL EAGERVAVIG PSGAGKTTLL
     RLAAGALQPD VGTVRFDGSS STGSTATLAY QGETLVDRRT ALSNVLTGRL GALSWLRGFI
     EPLLPQHPEP ALERLDAVGL VGRADVPVKS LSAGERQRVA FARALMQDAE VVLADEPTAN
     LDPSSRRNVI DVLDAALDGE LLVTVLHEVD LALEHFDRIV GMADGRVRFD TPARAVTDDQ
     LDALFAAGAS TPGTDAERTG TEKESDIPVP WYV