ID   PHNC1_HALWD             Reviewed;         304 AA.
AC   Q18KE1;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Phosphonates import ATP-binding protein PhnC 1 {ECO:0000255|HAMAP-Rule:MF_01713};
DE            EC=7.3.2.2 {ECO:0000255|HAMAP-Rule:MF_01713};
GN   Name=phnC1 {ECO:0000255|HAMAP-Rule:MF_01713}; OrderedLocusNames=HQ_1382A;
OS   Haloquadratum walsbyi (strain DSM 16790 / HBSQ001).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloquadratum.
OX   NCBI_TaxID=362976;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16790 / HBSQ001;
RX   PubMed=16820047; DOI=10.1186/1471-2164-7-169;
RA   Bolhuis H., Palm P., Wende A., Falb M., Rampp M., Rodriguez-Valera F.,
RA   Pfeiffer F., Oesterhelt D.;
RT   "The genome of the square archaeon Haloquadratum walsbyi: life at the
RT   limits of water activity.";
RL   BMC Genomics 7:169-169(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex PhnCDE involved in
CC       phosphonates import. Responsible for energy coupling to the transport
CC       system. {ECO:0000255|HAMAP-Rule:MF_01713}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + phosphonate(out) = ADP + H(+) + phosphate +
CC         phosphonate(in); Xref=Rhea:RHEA:18065, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:16215, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=7.3.2.2;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01713};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (PhnC),
CC       two transmembrane proteins (PhnE) and a solute-binding protein (PhnD).
CC       {ECO:0000255|HAMAP-Rule:MF_01713}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01713};
CC       Peripheral membrane protein {ECO:0000255|HAMAP-Rule:MF_01713}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Phosphonates
CC       importer (TC 3.A.1.9.1) family. {ECO:0000255|HAMAP-Rule:MF_01713}.
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DR   EMBL; AM180088; CAJ51510.1; -; Genomic_DNA.
DR   RefSeq; WP_011570665.1; NC_008212.1.
DR   AlphaFoldDB; Q18KE1; -.
DR   SMR; Q18KE1; -.
DR   STRING; 362976.HQ_1382A; -.
DR   EnsemblBacteria; CAJ51510; CAJ51510; HQ_1382A.
DR   GeneID; 4194447; -.
DR   KEGG; hwa:HQ_1382A; -.
DR   eggNOG; arCOG00206; Archaea.
DR   HOGENOM; CLU_000604_1_22_2; -.
DR   OMA; RDRIGFM; -.
DR   Proteomes; UP000001975; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015416; F:ABC-type phosphonate transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   CDD; cd03256; ABC_PhnC_transporter; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR012693; ABC_transpr_PhnC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51249; PHNC; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Phosphonate transport; Reference proteome; Translocase; Transport.
FT   CHAIN           1..304
FT                   /note="Phosphonates import ATP-binding protein PhnC 1"
FT                   /id="PRO_0000274771"
FT   DOMAIN          4..240
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01713"
FT   REGION          240..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        259..288
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         37..44
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01713"
SQ   SEQUENCE   304 AA;  32257 MW;  8887C9A63D3954CB CRC64;
     MPHVSLQNVT KLFGEDTIAL DDVSIEITAG EFVVILGPSG AGKSTLLRIL NGLTEPTTGT
     AQIGGSPVSE SGSDVGMVFQ MHYLIESLSA YRNALTGALS RTTNLKSILT LNQTDDKRAA
     LRALDTVGLL KDAEQRAGTM SGGQKQRVGI ARALVQNPSL LLADEPVSSL DPKAARDVMR
     YMKQAARERE LTTVASLHQV NIAREFGDRF IGVRDGTVIF DGSRAELSMD VIDDLYYAGS
     ESTPVSHGDI EGQGEGLTKP DDTSVSSDME TTSGRDHSTG TDTGTDTGTD TETDTETDTG
     EAQL