ID   PHNH_RHIME              Reviewed;         200 AA.
AC   Q52985;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH;
DE            Short=RPnTP synthase subunit PhnH;
DE            EC=2.7.8.37;
GN   Name=phnH; OrderedLocusNames=RB1452; ORFNames=SMb20760;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymB (megaplasmid 2).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RA   McLean P.A., Liu C.M., Sookdeo C.C., Cannon F.C.;
RT   "Characterization of a gene cluster involved in utilization of glyphosate
RT   and other phosphonates in Rhizobium meliloti.";
RL   Submitted (NOV-1992) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481431; DOI=10.1073/pnas.161294698;
RA   Finan T.M., Weidner S., Wong K., Buhrmester J., Chain P., Vorhoelter F.J.,
RA   Hernandez-Lucas I., Becker A., Cowie A., Gouzy J., Golding B., Puehler A.;
RT   "The complete sequence of the 1,683-kb pSymB megaplasmid from the N2-fixing
RT   endosymbiont Sinorhizobium meliloti.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9889-9894(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: Together with PhnG, PhnI and PhnL is required for the
CC       transfer of the ribose triphosphate moiety from ATP to methyl
CC       phosphonate. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + methylphosphonate = adenine + alpha-D-ribose 1-
CC         methylphosphonate 5-triphosphate; Xref=Rhea:RHEA:34679,
CC         ChEBI:CHEBI:16708, ChEBI:CHEBI:30616, ChEBI:CHEBI:68684,
CC         ChEBI:CHEBI:68823; EC=2.7.8.37;
CC   -!- SIMILARITY: Belongs to the PhnH family. {ECO:0000305}.
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DR   EMBL; M96263; AAA26351.1; -; Genomic_DNA.
DR   EMBL; AL591985; CAC49852.1; -; Genomic_DNA.
DR   PIR; D96023; D96023.
DR   RefSeq; NP_437992.1; NC_003078.1.
DR   RefSeq; WP_010976254.1; NC_003078.1.
DR   AlphaFoldDB; Q52985; -.
DR   SMR; Q52985; -.
DR   STRING; 266834.SM_b20760; -.
DR   EnsemblBacteria; CAC49852; CAC49852; SM_b20760.
DR   GeneID; 61601361; -.
DR   KEGG; sme:SM_b20760; -.
DR   PATRIC; fig|266834.11.peg.6378; -.
DR   eggNOG; COG3625; Bacteria.
DR   HOGENOM; CLU_115317_1_0_5; -.
DR   OMA; HDTPVWL; -.
DR   Proteomes; UP000001976; Plasmid pSymB.
DR   GO; GO:0061693; F:alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019634; P:organic phosphonate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.11310; -; 1.
DR   InterPro; IPR038058; PhnH-like_sp.
DR   InterPro; IPR008772; Phosphonate_metab_PhnH.
DR   Pfam; PF05845; PhnH; 1.
DR   PIRSF; PIRSF020680; PhnH; 1.
DR   SUPFAM; SSF159709; SSF159709; 1.
DR   TIGRFAMs; TIGR03292; PhnH_redo; 1.
PE   3: Inferred from homology;
KW   Plasmid; Reference proteome; Transferase.
FT   CHAIN           1..200
FT                   /note="Alpha-D-ribose 1-methylphosphonate 5-triphosphate
FT                   synthase subunit PhnH"
FT                   /id="PRO_0000058394"
SQ   SEQUENCE   200 AA;  21253 MW;  3CE648F736F5AFC1 CRC64;
     MTAQSQIYSG AFADPVFEAQ SVFRSLMDCF ARPGIIGRLS TAAAPPAPLG EASGAVALTL
     CDHDTPVWLS PALSKSSAPK WIAFHTGAGV TDTKDEPRFA FFEKGAAVPG FDQFALGTQE
     YPDRSTTLVV EVEALEGGQP LIGRGPGIKN GIVIAPKGLP DVFLDLWAAN RAIFPRGIDL
     VLTAREAVLC LPRTTKLERE