ID   PHNT_SALTI              Reviewed;         369 AA.
AC   Q8Z8W8; Q7C879;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Putative 2-aminoethylphosphonate import ATP-binding protein PhnT;
GN   Name=phnT; OrderedLocusNames=STY0467, t2435;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved
CC       in 2-aminoethylphosphonate import. Probably responsible for energy
CC       coupling to the transport system (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Peripheral
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. 2-
CC       aminoethylphosphonate importer (TC 3.A.1.11.5) family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD08884.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO70025.1; -; Genomic_DNA.
DR   RefSeq; NP_455022.1; NC_003198.1.
DR   RefSeq; WP_000928794.1; NZ_WSUR01000026.1.
DR   AlphaFoldDB; Q8Z8W8; -.
DR   SMR; Q8Z8W8; -.
DR   STRING; 220341.16501696; -.
DR   EnsemblBacteria; AAO70025; AAO70025; t2435.
DR   KEGG; stt:t2435; -.
DR   KEGG; sty:STY0467; -.
DR   PATRIC; fig|220341.7.peg.468; -.
DR   eggNOG; COG3842; Bacteria.
DR   HOGENOM; CLU_000604_1_1_6; -.
DR   OMA; HITAIHV; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR017662; AminoethylPonate_ABC_PhnT.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR03258; PhnT; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Transport.
FT   CHAIN           1..369
FT                   /note="Putative 2-aminoethylphosphonate import ATP-binding
FT                   protein PhnT"
FT                   /id="PRO_0000286741"
FT   DOMAIN          19..250
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         51..58
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   369 AA;  40091 MW;  3DAB233F0F5498F6 CRC64;
     MLMKTTAVHA PASQGTSGIV LDSLRVAYHG NVVLKPLSLT IEPGEVLALI GPSGSGKTTV
     LRAVAGFVQP AGGRILIGDT DVTHLPPYKR GLAMVVQNYA LFPHLKVEDN VAFGLRAQKQ
     PKALINERVT QALKTVGMSD YATRYPHQLS GGQQQRVAIA RAIAVRPRVL LLDEPLSALD
     AQIRHNMVEE IARLHRELPE LTILYVTHDQ TEALTLADKI GIMKDGSLIA HGETRALYHH
     PPNRFAAEFL GRANILSAIA LGITEVPGLV DVSCGGAVIR AFSQGSHHGY NKLLCIRPQH
     LSLTPRSAYS NRFNATLQSV HWQGDLTHLL CDVAGETVRM VLTHVNPLPR VGDKLALWFE
     PDDAVLIEV