ID   PHNU_SALPA              Reviewed;         289 AA.
AC   Q5PFQ6;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative 2-aminoethylphosphonate transport system permease protein PhnU;
GN   Name=phnU; OrderedLocusNames=SPA2296;
OS   Salmonella paratyphi A (strain ATCC 9150 / SARB42).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=295319;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9150 / SARB42;
RX   PubMed=15531882; DOI=10.1038/ng1470;
RA   McClelland M., Sanderson K.E., Clifton S.W., Latreille P., Porwollik S.,
RA   Sabo A., Meyer R., Bieri T., Ozersky P., McLellan M., Harkins C.R.,
RA   Wang C., Nguyen C., Berghoff A., Elliott G., Kohlberg S., Strong C., Du F.,
RA   Carter J., Kremizki C., Layman D., Leonard S., Sun H., Fulton L., Nash W.,
RA   Miner T., Minx P., Delehaunty K., Fronick C., Magrini V., Nhan M.,
RA   Warren W., Florea L., Spieth J., Wilson R.K.;
RT   "Comparison of genome degradation in Paratyphi A and Typhi, human-
RT   restricted serovars of Salmonella enterica that cause typhoid.";
RL   Nat. Genet. 36:1268-1274(2004).
CC   -!- FUNCTION: Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved
CC       in 2-aminoethylphosphonate import. Probably responsible for the
CC       translocation of the substrate across the membrane (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
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DR   EMBL; CP000026; AAV78181.1; -; Genomic_DNA.
DR   RefSeq; WP_000052714.1; NC_006511.1.
DR   AlphaFoldDB; Q5PFQ6; -.
DR   SMR; Q5PFQ6; -.
DR   EnsemblBacteria; AAV78181; AAV78181; SPA2296.
DR   KEGG; spt:SPA2296; -.
DR   HOGENOM; CLU_016047_18_0_6; -.
DR   OMA; TPFVMRP; -.
DR   Proteomes; UP000008185; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0033223; P:2-aminoethylphosphonate transport; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR017636; AminoethylPonate_ABC_perm-PhnU.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR03226; PhnU; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..289
FT                   /note="Putative 2-aminoethylphosphonate transport system
FT                   permease protein PhnU"
FT                   /id="PRO_0000286744"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          68..275
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   289 AA;  31190 MW;  9532F870E81A5DFC CRC64;
     MSLILPLEKP ALNLRPLLWL LLPLLVLATL FFWPLSLIVE QALRGANGEI GLETFRQVVD
     SKRFVGALLN TLQIAFFATA GCLLLGSVMS LILVFIPFPG SELIGRVVDT FIALPTFLIT
     LAFTFIYGSA GLLNGALMSL FAFELPPVDF LYSMQGVILA EITVFTPLVM RPLMAALRQI
     DKSQLEAASI LGAHPLRVIG QVIFPAALPA LMAGGSLCLL LTTNEFGIVL FIGAKGVNTL
     PMMVYSKAIL ESDYTVACMI ALINIVLSLG LFSLYRLAAS RTGVRSQPC