ID   PHNV_SALTY              Reviewed;         265 AA.
AC   P96065; Q7CR34;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Putative 2-aminoethylphosphonate transport system permease protein PhnV;
GN   Name=phnV; OrderedLocusNames=STM0426;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RA   Metcalf W.W., Jiang W., Wanner B.L.;
RT   "Molecular genetic analysis of the Salmonella typhimurium LT2 phnXWRSTUV
RT   locus required for 2-aminoethylphosphonate transport and metabolism.";
RL   Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [3]
RP   CLONING, AND INDUCTION.
RC   STRAIN=LT2;
RX   PubMed=7592415; DOI=10.1128/jb.177.22.6411-6421.1995;
RA   Jiang W., Metcalf W.W., Lee K.-S., Wanner B.L.;
RT   "Molecular cloning, mapping, and regulation of Pho regulon genes for
RT   phosphonate breakdown by the phosphonatase pathway of Salmonella
RT   typhimurium LT2.";
RL   J. Bacteriol. 177:6411-6421(1995).
CC   -!- FUNCTION: Probably part of the PhnSTUV complex (TC 3.A.1.11.5) involved
CC       in 2-aminoethylphosphonate import. Probably responsible for the
CC       translocation of the substrate across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- INDUCTION: Induced when inorganic phosphate is limiting; this is
CC       controlled by PhoB. {ECO:0000269|PubMed:7592415}.
CC   -!- MISCELLANEOUS: Maps to a phosphate-starvation-inducible locus
CC       previously known as psiC.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. {ECO:0000305}.
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DR   EMBL; U69493; AAB39647.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL19380.1; -; Genomic_DNA.
DR   PIR; T46952; T46952.
DR   RefSeq; NP_459421.1; NC_003197.2.
DR   RefSeq; WP_000909791.1; NC_003197.2.
DR   AlphaFoldDB; P96065; -.
DR   SMR; P96065; -.
DR   STRING; 99287.STM0426; -.
DR   TCDB; 3.A.1.11.5; the atp-binding cassette (abc) superfamily.
DR   PaxDb; P96065; -.
DR   EnsemblBacteria; AAL19380; AAL19380; STM0426.
DR   GeneID; 1251945; -.
DR   KEGG; stm:STM0426; -.
DR   PATRIC; fig|99287.12.peg.455; -.
DR   HOGENOM; CLU_016047_3_2_6; -.
DR   OMA; LGGTKWI; -.
DR   PhylomeDB; P96065; -.
DR   BioCyc; SENT99287:STM0426-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR017661; AminoethylPonate_ABC_PhnV.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   TIGRFAMs; TIGR03255; PhnV; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   2: Evidence at transcript level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..265
FT                   /note="Putative 2-aminoethylphosphonate transport system
FT                   permease protein PhnV"
FT                   /id="PRO_0000286750"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        69..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        131..151
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        233..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          65..253
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   265 AA;  28470 MW;  B7598A519F94EC32 CRC64;
     MLIWSPKGRA AAGVVASVLF IVFFFLPLAV ILMSSLSQQW NGILPSGFTL NHFVNALHGA
     AWDALLASLT IGFCASLFAL LCGVWAALAL RQYGVKTQKW LSMVFYLPSA IPSVSVGLGI
     LVAFSQGPLQ MNGTLWIVLT AHFVLISAFT FSNVSTGLAR ISADIENVAS SLGASPWYRL
     RHVTLPLLMP WMMSALALSL SLSMGELGAT MMIYPPGWTT LPVAIFSLTD RGNIADGAAL
     TIVLVAITLL LMMKLERIAK RLGQK