ID   PHNXL_SYNFM             Reviewed;         277 AA.
AC   A0LJ16;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Phosphonoacetaldehyde hydrolase-like protein;
GN   Name=phnX2; OrderedLocusNames=Sfum_1731;
OS   Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Syntrophobacterales;
OC   Syntrophobacteraceae; Syntrophobacter.
OX   NCBI_TaxID=335543;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 10017 / MPOB;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.G.,
RA   Martinez M., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Kim E., Boone D.R., Brockman F., Culley D., Ferry J., Gunsalus R.,
RA   McInerney M.J., Morrison M., Plugge C., Rohlin L., Scholten J., Sieber J.,
RA   Stams A.J.M., Worm P., Henstra A.M., Richardson P.;
RT   "Complete sequence of Syntrophobacter fumaroxidans MPOB.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily. PhnX family.
CC       {ECO:0000305}.
CC   -!- CAUTION: Arg-61 is present instead of the conserved Lys which is
CC       expected to be an active site residue. The same site-directed mutant in
CC       B.cereus has no activity; therefore this protein is probably inactive.
CC       {ECO:0000305}.
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DR   EMBL; CP000478; ABK17418.1; -; Genomic_DNA.
DR   RefSeq; WP_011698588.1; NC_008554.1.
DR   AlphaFoldDB; A0LJ16; -.
DR   SMR; A0LJ16; -.
DR   STRING; 335543.Sfum_1731; -.
DR   EnsemblBacteria; ABK17418; ABK17418; Sfum_1731.
DR   KEGG; sfu:Sfum_1731; -.
DR   eggNOG; COG0637; Bacteria.
DR   HOGENOM; CLU_045011_12_0_7; -.
DR   OMA; TWPGILE; -.
DR   OrthoDB; 1484726at2; -.
DR   Proteomes; UP000001784; Chromosome.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0050194; F:phosphonoacetaldehyde hydrolase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019700; P:organic phosphonate catabolic process; IEA:InterPro.
DR   CDD; cd02586; HAD_PHN; 1.
DR   Gene3D; 1.10.150.240; -; 1.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   HAMAP; MF_01375; PhnX; 1.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR041492; HAD_2.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR023198; PGP-like_dom2.
DR   InterPro; IPR006323; Phosphonoacetald_hydro.
DR   Pfam; PF13419; HAD_2; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR01422; phosphonatase; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..277
FT                   /note="Phosphonoacetaldehyde hydrolase-like protein"
FT                   /id="PRO_0000284608"
SQ   SEQUENCE   277 AA;  30476 MW;  AA17A000DF0F7290 CRC64;
     MEVFSRSNPY RGPVKGVVLD WAGTTVDYGC IGPLSVFVEV FRHNWVEVTI EEARAPMGLS
     REDHLRAMCR AESVARKWED VHGAPPSEMD IGNMARMVEA HLAYTIAQHA DLIPGVVEAV
     EALRGQGIRI GSSTGYTSDM MDMLVPAVEE NGYRPDSIVC ASDVPAGRPF PWMCYQNAIN
     LEVYPMAAMV KIGDTVADIR EGLNAGMWTI GLTLTGNELG LSEEEVAAMD PEELRRRMDN
     IEQRFRNAGA HFVAQGLRDC PAVIRDINEL LAGGERP