ID   PHO11_ORYSJ             Reviewed;         799 AA.
AC   Q657S5; A0A0P0UWZ7;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 2.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Phosphate transporter PHO1-1;
DE   AltName: Full=Protein PHO1-1;
DE            Short=OsPHO1;1;
GN   Name=PHO1-1; OrderedLocusNames=Os01g0110100, LOC_Os01g02000;
GN   ORFNames=P0439B06.4, P0482C06.38;
OS   Oryza sativa subsp. japonica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39947;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=12447438; DOI=10.1038/nature01184;
RA   Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA   Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA   Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA   Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA   Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA   Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA   Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA   Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA   Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA   Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA   Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA   Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA   Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT   "The genome sequence and structure of rice chromosome 1.";
RL   Nature 420:312-316(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Nipponbare;
RX   PubMed=16100779; DOI=10.1038/nature03895;
RG   International rice genome sequencing project (IRGSP);
RT   "The map-based sequence of the rice genome.";
RL   Nature 436:793-800(2005).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Nipponbare;
RX   PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA   Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA   Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA   Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA   Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT   "Improvement of the Oryza sativa Nipponbare reference genome using next
RT   generation sequence and optical map data.";
RL   Rice 6:4-4(2013).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Nipponbare;
RG   The rice full-length cDNA consortium;
RT   "Oryza sativa full length cDNA.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   TISSUE SPECIFICITY, INDUCTION, GENE FAMILY, NOMENCLATURE, AND DISRUPTION
RP   PHENOTYPE.
RX   PubMed=20081045; DOI=10.1104/pp.109.149872;
RA   Secco D., Baumann A., Poirier Y.;
RT   "Characterization of the rice PHO1 gene family reveals a key role for
RT   OsPHO1;2 in phosphate homeostasis and the evolution of a distinct clade in
RT   dicotyledons.";
RL   Plant Physiol. 152:1693-1704(2010).
CC   -!- FUNCTION: May transport inorganic phosphate (Pi). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots and flowers.
CC       {ECO:0000269|PubMed:20081045}.
CC   -!- INDUCTION: By Pi deficiency in roots. {ECO:0000269|PubMed:20081045}.
CC   -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC       {ECO:0000269|PubMed:20081045}.
CC   -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAD44869.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC       Sequence=BAD44936.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AP002845; BAD44869.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP002882; BAD44936.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AP014957; BAS70005.1; -; Genomic_DNA.
DR   EMBL; AK242852; -; NOT_ANNOTATED_CDS; mRNA.
DR   RefSeq; XP_015623371.1; XM_015767885.1.
DR   AlphaFoldDB; Q657S5; -.
DR   STRING; 4530.OS01T0110100-01; -.
DR   PaxDb; Q657S5; -.
DR   PRIDE; Q657S5; -.
DR   EnsemblPlants; Os01t0110100-01; Os01t0110100-01; Os01g0110100.
DR   GeneID; 9270401; -.
DR   Gramene; Os01t0110100-01; Os01t0110100-01; Os01g0110100.
DR   KEGG; osa:9270401; -.
DR   eggNOG; KOG1162; Eukaryota.
DR   HOGENOM; CLU_006116_2_0_1; -.
DR   InParanoid; Q657S5; -.
DR   OMA; FWLSFAR; -.
DR   OrthoDB; 536327at2759; -.
DR   Proteomes; UP000000763; Chromosome 1.
DR   Proteomes; UP000059680; Chromosome 1.
DR   Genevisible; Q657S5; OS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0000822; F:inositol hexakisphosphate binding; IBA:GO_Central.
DR   GO; GO:0015114; F:phosphate ion transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0016036; P:cellular response to phosphate starvation; IBA:GO_Central.
DR   GO; GO:0006817; P:phosphate ion transport; IBA:GO_Central.
DR   CDD; cd14476; SPX_PHO1_like; 1.
DR   InterPro; IPR004342; EXS_C.
DR   InterPro; IPR034092; PHO1_SPX.
DR   InterPro; IPR004331; SPX_dom.
DR   Pfam; PF03124; EXS; 1.
DR   Pfam; PF03105; SPX; 1.
DR   PROSITE; PS51380; EXS; 1.
DR   PROSITE; PS51382; SPX; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Phosphate transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..799
FT                   /note="Phosphate transporter PHO1-1"
FT                   /id="PRO_0000398165"
FT   TOPO_DOM        1..406
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        407..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        428..447
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        448..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        469..492
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        493..513
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        514..522
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        523..543
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        544..672
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        673..693
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        694..718
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        719..739
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        740..799
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          2..354
FT                   /note="SPX"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00714"
FT   DOMAIN          608..799
FT                   /note="EXS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00712"
FT   REGION          170..243
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..226
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   799 AA;  91192 MW;  4473F0D95FC52214 CRC64;
     MVKFSKQFEG QLVPEWKHAF VDYSLLKKDL KRMQHDYSPQ GTIITTSTPH DHHQQQQSVA
     APSSYNLSHC RLLLHKLPAA FFGSNNADHA GAIQVRRRVG RGEVYETEVT PEMETTAATA
     AREFFARLDA QLNKVNHFYK AKEEEFLHRG HSLRKQMDIL LDLKSRSSSS LSGHHRAAAG
     DDPSISSSSA TSGAEDESTR YVTSATDTDE SQHETAVMRD PEELSAEQGL EDSGSLSRQS
     LGRTVSSCQR KNLKINIPLT TPCRTISALT DLLRDDLVSQ PKNKCDSDAG ITFTTINKTK
     LRHAEKMIKG AFIELYKGLG YLTTYRNLNM MAFVKILKKF EKVSGKQVLS VYLRAVESSY
     FNSSGEALKL MDEVEDVFVR HFAAGNRRKA MKYLKPTQRK ESHTVTFFIG LMTGCFVALF
     LGYCIMAHIA GMYTQRRDSI YMETVYPVFS MFSLMFLHLF MYGCNMVAWR KARINYSFIF
     EFAAGRELKY RDVFLVCTAS MAVIVGVMFA HLSLAVRGFH AQAIPGFLLL GFLLLLFCPF
     NMVYRSTRFQ FLRILRNIVF SPLYKVVMVD FFMADQLCSQ VPMLRSLEYV ACYYISGSYR
     TQEYGYCINT KHIRDLAYAV SFLPYYWRAM QCARRWFDES DTGHLVNLGK YVSAMLAAGA
     KVAYEKDRSL GSLSLLVIVS SSATMYQLYW DFVKDWGLLQ PNSKNPWLRN DLILKSKSIY
     YLSMGLNLVL RLAWLQTVIH PNFGSLDSRV TSFFLAALEV IRRGHWNFYR LENEHLNNAG
     KFRAVKTVPL PFHEADEED