PHO17_ARATH
ID PHO17_ARATH Reviewed; 750 AA.
AC Q6R8G3; Q9LQX9;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Phosphate transporter PHO1 homolog 7;
DE AltName: Full=Protein PHO1 homolog 7;
DE Short=AtPHO1;H7;
GN Name=PHO1-H7; OrderedLocusNames=At1g26730; ORFNames=T24P13.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, INDUCTION, GENE FAMILY, AND
RP NOMENCLATURE.
RX PubMed=15122012; DOI=10.1104/pp.103.037945;
RA Wang Y., Ribot C., Rezzonico E., Poirier Y.;
RT "Structure and expression profile of the Arabidopsis PHO1 gene family
RT indicates a broad role in inorganic phosphate homeostasis.";
RL Plant Physiol. 135:400-411(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: May transport inorganic phosphate (Pi). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in root tips, vascular cylinders of roots
CC and filaments, leaf hydathodes, stem, receptacle and stigma apex.
CC {ECO:0000269|PubMed:15122012}.
CC -!- INDUCTION: Not induced by Pi deficiency. {ECO:0000269|PubMed:15122012}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF87029.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AY507959; AAR99489.1; -; mRNA.
DR EMBL; AC006535; AAF87029.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30725.1; -; Genomic_DNA.
DR RefSeq; NP_173995.1; NM_102436.2.
DR AlphaFoldDB; Q6R8G3; -.
DR BioGRID; 24450; 1.
DR STRING; 3702.AT1G26730.1; -.
DR iPTMnet; Q6R8G3; -.
DR PaxDb; Q6R8G3; -.
DR PRIDE; Q6R8G3; -.
DR ProteomicsDB; 235081; -.
DR EnsemblPlants; AT1G26730.1; AT1G26730.1; AT1G26730.
DR GeneID; 839214; -.
DR Gramene; AT1G26730.1; AT1G26730.1; AT1G26730.
DR KEGG; ath:AT1G26730; -.
DR Araport; AT1G26730; -.
DR TAIR; locus:2200575; AT1G26730.
DR eggNOG; KOG1162; Eukaryota.
DR HOGENOM; CLU_006116_2_0_1; -.
DR InParanoid; Q6R8G3; -.
DR OMA; NCCQEIQ; -.
DR OrthoDB; 536327at2759; -.
DR PhylomeDB; Q6R8G3; -.
DR PRO; PR:Q6R8G3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q6R8G3; baseline and differential.
DR Genevisible; Q6R8G3; AT.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005802; C:trans-Golgi network; IBA:GO_Central.
DR GO; GO:0000822; F:inositol hexakisphosphate binding; IBA:GO_Central.
DR GO; GO:0015114; F:phosphate ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0016036; P:cellular response to phosphate starvation; IBA:GO_Central.
DR GO; GO:0006817; P:phosphate ion transport; IBA:GO_Central.
DR CDD; cd14476; SPX_PHO1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR034092; PHO1_SPX.
DR InterPro; IPR004331; SPX_dom.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Phosphate transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..750
FT /note="Phosphate transporter PHO1 homolog 7"
FT /id="PRO_0000398161"
FT TOPO_DOM 1..350
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 372..391
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 392..412
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 413..435
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 436..456
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 457..472
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 473..493
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 494..622
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 623..643
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 644..666
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 667..687
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 688..750
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 1..298
FT /note="SPX"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00714"
FT DOMAIN 557..750
FT /note="EXS"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00712"
SQ SEQUENCE 750 AA; 87333 MW; 354BF5CAD552CAA4 CRC64;
MKFGKDFVRQ MIPEWQQAYM DYAGLKSILQ EIQTSRKRSE RPGILKRKLS GSRNFSGLTK
RYSRTASTRE PEIQDILVHA TTGDDGFERY ETTILEVAEA GRESELAFFK TLDLEFDKVN
HFYRSKVEEM VKEAVVLNKQ MDALIAFRIK VERPSSSWSC SETVSVDMNA LDSNDQRNTL
AEEMGIRVEG NGSNGGDSTK ESVPQVLSVL ERIRLNKTQE TPLSTIKNVL KLSNQEELKF
TRENLKKIEE RLKNVFIEFY RKLRHLKNYS FLNTLAISKI MKKYDKIASR SAAKPYMEMV
DKSYLTSSDE INKLMLRVES TFVEHFAGLN RSKGMNLLRP KVKKEKHRIT FSTGFFVGCT
VSLVVALVMF IHARNIMGAV GHKVYMETMF PLYSLFAFVV LHMIMYASNI YFWKRYRVNY
PFIFGFKEGT ELGYRHVLLL SFGLGTLALC AVLINLDMEM DPNTNDYKTM TELLPMFILA
LVVAILFCPF NIFYRSSRVF FLMVVFRCIA APLYKVNLPD FFLADQLTSQ VQALRSLEFY
ICYYGWGDFK HRQNTCRSSD VYSTFYFIVA VIPYWSRFLQ CVRRLIEEND SSQGYNALKY
LLTVVAVCLR TAYSFNRGNI WKISAWVFSA LATFYGTYWD IVFDWGLLHR PSKHLLREKL
LVPHKAVYYV AIVLNIVLRM AWLQTVLDFN LSFLHRETMI ALLAALEIIR RGIWNFFRLE
NEHLNNVGKF RAFKSVPLPF NYNEEEDRDS
