PHOCN_CAEEL
ID PHOCN_CAEEL Reviewed; 223 AA.
AC P34349;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2003, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=MOB-like protein phocein {ECO:0000305};
DE AltName: Full=Mps one binder 4 homolog {ECO:0000312|WormBase:C30A5.3};
GN Name=mob-4 {ECO:0000312|WormBase:C30A5.3};
GN ORFNames=C30A5.3 {ECO:0000312|WormBase:C30A5.3};
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: May play a role in membrane trafficking, specifically in
CC membrane budding reactions. {ECO:0000250|UniProtKB:Q9QYW3}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, perinuclear region
CC {ECO:0000250|UniProtKB:Q9Y3A3}. Membrane
CC {ECO:0000250|UniProtKB:Q9Y3A3}; Peripheral membrane protein
CC {ECO:0000250|UniProtKB:Q9Y3A3}. Golgi apparatus, Golgi stack membrane
CC {ECO:0000250|UniProtKB:Q9Y3A3}; Peripheral membrane protein
CC {ECO:0000250|UniProtKB:Q9Y3A3}.
CC -!- SIMILARITY: Belongs to the MOB1/phocein family. {ECO:0000305}.
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DR EMBL; BX284603; CCD62652.1; -; Genomic_DNA.
DR PIR; S44776; S44776.
DR RefSeq; NP_498798.2; NM_066397.4.
DR AlphaFoldDB; P34349; -.
DR SMR; P34349; -.
DR BioGRID; 41363; 2.
DR STRING; 6239.C30A5.3; -.
DR EPD; P34349; -.
DR PaxDb; P34349; -.
DR PeptideAtlas; P34349; -.
DR EnsemblMetazoa; C30A5.3.1; C30A5.3.1; WBGene00016238.
DR GeneID; 176158; -.
DR KEGG; cel:CELE_C30A5.3; -.
DR UCSC; C30A5.3.1; c. elegans.
DR CTD; 176158; -.
DR WormBase; C30A5.3; CE32154; WBGene00016238; mob-4.
DR eggNOG; KOG1852; Eukaryota.
DR GeneTree; ENSGT01050000244956; -.
DR HOGENOM; CLU_056981_3_0_1; -.
DR InParanoid; P34349; -.
DR OMA; CKRFTTY; -.
DR OrthoDB; 1229701at2759; -.
DR PhylomeDB; P34349; -.
DR PRO; PR:P34349; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00016238; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.140.30; -; 1.
DR InterPro; IPR005301; MOB_kinase_act_fam.
DR InterPro; IPR036703; MOB_kinase_act_sf.
DR PANTHER; PTHR22599; PTHR22599; 1.
DR Pfam; PF03637; Mob1_phocein; 1.
DR SMART; SM01388; Mob1_phocein; 1.
DR SUPFAM; SSF101152; SSF101152; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Golgi apparatus; Membrane; Metal-binding; Reference proteome;
KW Transport; Zinc.
FT CHAIN 1..223
FT /note="MOB-like protein phocein"
FT /id="PRO_0000065205"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 92
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9H8S9"
FT BINDING 97
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9H8S9"
FT BINDING 169
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9H8S9"
FT BINDING 174
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9H8S9"
SQ SEQUENCE 223 AA; 25895 MW; 0D439928362C98DF CRC64;
MTAATENRTV RRNGPGTKRA DWNNWSPLAF EEMDSALNIQ QYIQQTIKAN PADVATILTP
PLDQDEGVWK YEHLRQFCIE LNGLALLLQR ECIPETCQQM TATEQWIFLC AAHKNPNECP
AIDYTRHTLD GAATLLNSNK YFPSRVNIKE ISISKLGSVA RRVYRIFSHA FFHHRKLFDE
FENETHLCKR FTTYVSKYNL MQQEHLIVPI LPNQQQQQQT TVQ
