ID   PHOE_CITFR              Reviewed;         351 AA.
AC   Q01605;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Outer membrane porin PhoE;
DE   AltName: Full=Outer membrane pore protein E;
DE   Flags: Precursor;
GN   Name=phoE;
OS   Citrobacter freundii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
OX   NCBI_TaxID=546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1337052; DOI=10.1016/0378-1097(92)90025-j;
RA   Spierings G., Ockhuijsen C., Hofstra H., Tommassen J.;
RT   "Characterization of the Citrobacter freundii phoE gene and development of
RT   C. freundii-specific oligonucleotides.";
RL   FEMS Microbiol. Lett. 78:199-204(1992).
CC   -!- FUNCTION: Uptake of inorganic phosphate, phosphorylated compounds, and
CC       some other negatively charged solutes.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- INDUCTION: By phosphate starvation.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; X68021; CAA48162.1; -; Genomic_DNA.
DR   PIR; S25520; S25520.
DR   AlphaFoldDB; Q01605; -.
DR   SMR; Q01605; -.
DR   STRING; 1333848.CFNIH1_11120; -.
DR   PRIDE; Q01605; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal;
KW   Stress response; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..21
FT   CHAIN           22..351
FT                   /note="Outer membrane porin PhoE"
FT                   /id="PRO_0000025241"
SQ   SEQUENCE   351 AA;  38807 MW;  4E9C144070381B5A CRC64;
     MKKSTLALVV MGITASASVQ AAEVYNKNGN KLDLYGKVKA MHYMTDYDSK DGDQSYIRLG
     FKGETQINDE LTGYGRWEAE FAGNKAESDS NQQKTRLAFA GSKLKNLGSF DYGRNLGALY
     DVEAWTDMFP EFGGDSSAQT DNFMTKRASG LATYRNTDFF GVVDGLDLTL QYQGKNQDRD
     VKKQNGDGFG TSVTYDFGGS DFAVSGAYTN SDRTNQQNLQ TRGTGDKAEA WATGLKYDAN
     DIYIATFYSE TRNMTPISGG FANKTQNFEA VVQYQFDFGL RPSLGYVLSK GKDIEGVGNE
     DLVNYIDVGA TYYFNKNMSA FVDYKINQLD SDNKLGINND DIVAVGMVYQ F