ID   PHOE_ENTCL              Reviewed;         350 AA.
AC   Q47490;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Outer membrane porin PhoE;
DE   AltName: Full=Outer membrane pore protein E;
DE   Flags: Precursor;
GN   Name=phoE;
OS   Enterobacter cloacae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Enterobacter; Enterobacter cloacae complex.
OX   NCBI_TaxID=550;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3032618; DOI=10.1111/j.1432-1033.1987.tb11080.x;
RA   van der Ley P., Bekkers A., van Meersbergen J., Tommassen J.;
RT   "A comparative study on the phoE genes of three enterobacterial species.
RT   Implications for structure-function relationships in a pore-forming protein
RT   of the outer membrane.";
RL   Eur. J. Biochem. 164:469-475(1987).
CC   -!- FUNCTION: Uptake of inorganic phosphate, phosphorylated compounds, and
CC       some other negatively charged solutes.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- INDUCTION: By phosphate starvation.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; M28296; AAA24809.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q47490; -.
DR   SMR; Q47490; -.
DR   STRING; 1399774.JDWH01000001_gene2573; -.
DR   eggNOG; COG3203; Bacteria.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal;
KW   Stress response; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000250"
FT   CHAIN           22..350
FT                   /note="Outer membrane porin PhoE"
FT                   /id="PRO_0000025243"
SQ   SEQUENCE   350 AA;  38511 MW;  101665FEECC3AFA4 CRC64;
     MKKSTLALVV MGVVASASVH AAEVYNKNGN KLDVYGKVKA MHYISDDDTK DGDQTYVRFG
     FKGETQINDQ LTGYGRWEAE FAGNKAESDS SQKTRLAFAG LKLKDFGSLD YGRNLGALYD
     VEAWTDMFPE FGGDSSAQTD NFMTKRASGL ATYRNTDFFG AIDGLDMTLQ YQGKNENRDA
     KKQNGDGFGT SLTYDFGGTD FAVSGAYTNS DRTNAQNLLA RAQGQKAEAW ATGLKYDAND
     IYLAAMYSET RNMTPISGGF ANKAQNFEVV AQYQFDFGLR PSLGYVQSKG KDNEGIGDED
     LVKYIDVGAT YYFNKNMSAF VDYKINQIDD DNKLGVSSDD IVAVGMTYQF