ID   PHOE_KLEOX              Reviewed;         349 AA.
AC   Q01606;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Outer membrane porin PhoE;
DE   AltName: Full=Outer membrane pore protein E;
DE   Flags: Precursor;
GN   Name=phoE;
OS   Klebsiella oxytoca.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=571;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K26;
RX   PubMed=1337052; DOI=10.1016/0378-1097(92)90025-j;
RA   Spierings G., Ockhuijsen C., Hofstra H., Tommassen J.;
RT   "Characterization of the Citrobacter freundii phoE gene and development of
RT   C. freundii-specific oligonucleotides.";
RL   FEMS Microbiol. Lett. 78:199-204(1992).
CC   -!- FUNCTION: Uptake of inorganic phosphate, phosphorylated compounds, and
CC       some other negatively charged solutes.
CC   -!- SUBUNIT: Homotrimer.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- INDUCTION: By phosphate starvation.
CC   -!- SIMILARITY: Belongs to the Gram-negative porin family. {ECO:0000305}.
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DR   EMBL; X68022; CAA48163.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q01606; -.
DR   SMR; Q01606; -.
DR   STRING; 571.MC52_13805; -.
DR   eggNOG; COG3203; Bacteria.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:InterPro.
DR   CDD; cd00342; gram_neg_porins; 1.
DR   Gene3D; 2.40.160.10; -; 1.
DR   InterPro; IPR033900; Gram_neg_porin_domain.
DR   InterPro; IPR023614; Porin_dom_sf.
DR   InterPro; IPR001897; Porin_gammaproteobac.
DR   InterPro; IPR001702; Porin_Gram-ve.
DR   InterPro; IPR013793; Porin_Gram-ve_CS.
DR   Pfam; PF00267; Porin_1; 1.
DR   PRINTS; PR00183; ECOLIPORIN.
DR   PRINTS; PR00182; ECOLNEIPORIN.
DR   PROSITE; PS00576; GRAM_NEG_PORIN; 1.
PE   2: Evidence at transcript level;
KW   Cell outer membrane; Ion transport; Membrane; Porin; Signal;
KW   Stress response; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..21
FT   CHAIN           22..349
FT                   /note="Outer membrane porin PhoE"
FT                   /id="PRO_0000025244"
SQ   SEQUENCE   349 AA;  38551 MW;  D0B0A5427542B3F5 CRC64;
     MKKSSLALMM MGLIASSATQ AAEVYNKNGN KLDVYGKVKA MHYMSDYDSK DGDQTYVRFG
     IKGETQINDD LTGYGRWESE FSGNKTESDS SQKTRLAFAG VKVKNYGSFD YGRNLGALYD
     VEAWTDMFPE FGGDSSAQTD NFMTKRASGL ATYRNTDFFG VVDGLDLTLQ YQGKNEGREA
     KKQNGDGFGT SLSYDFGGSD FAVSAAYTSS DRTNDQNLLA RGAKKAEAWA TGLKYDANNI
     YLATMYSETR KMTPISGGFA NKAQNFEAVA QYQFDFGLRP SLGYVLSKGK DIEGVGSEDL
     VNYIDVGVTY YFNKNMNAFV DYKINQLKSD NKLGINDDDI VAVGMTYQF