ID   PHOH_ECO57              Reviewed;         354 AA.
AC   P0A9K2; P31544;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Protein PhoH;
DE   AltName: Full=Phosphate starvation-inducible protein PsiH;
GN   Name=phoH; OrderedLocusNames=Z1522, ECs1266;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PhoH family. {ECO:0000305}.
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DR   EMBL; AE005174; AAG55638.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB34689.1; -; Genomic_DNA.
DR   PIR; B90787; B90787.
DR   RefSeq; NP_309293.1; NC_002695.1.
DR   RefSeq; WP_000258765.1; NZ_SEKU01000016.1.
DR   AlphaFoldDB; P0A9K2; -.
DR   SMR; P0A9K2; -.
DR   STRING; 155864.EDL933_1447; -.
DR   EnsemblBacteria; AAG55638; AAG55638; Z1522.
DR   EnsemblBacteria; BAB34689; BAB34689; ECs_1266.
DR   GeneID; 912858; -.
DR   KEGG; ece:Z1522; -.
DR   KEGG; ecs:ECs_1266; -.
DR   PATRIC; fig|386585.9.peg.1374; -.
DR   eggNOG; COG1702; Bacteria.
DR   HOGENOM; CLU_051654_4_0_6; -.
DR   OMA; EAQNCTY; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003714; PhoH.
DR   Pfam; PF02562; PhoH; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..354
FT                   /note="Protein PhoH"
FT                   /id="PRO_0000201151"
FT   BINDING         173..180
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   354 AA;  39265 MW;  28E5F229797EB41C CRC64;
     MVTSCTGHVL DNQRATTRGV FSSGSHLVTL HFQPHPFFSC VTDAVNGARS RFSAFYPKAN
     YGLQGSQPSD VRAHNRAANG ACDEYKQLKV LSMGRQKAVI KARREAKRVL RRDSRSHKQR
     EEESVTSLVQ MGGVEAIGMA RDSRDTSPIL ARNEAQLHYL KAIESKQLIF ATGEAGCGKT
     WISAAKAAEA LIHKDVDRII VTRPVLQADE DLGFLPGDIA EKFAPYFRPV YDVLVRRLGA
     SFMQYCLRPE IGKVEIAPFA YMRGRTFENA VVILDEAQNV TAAQMKMFLT RLGENVTVIV
     NGDITQCDLP RGVCSGLSDA LERFEEDEMV GIVRFGKEDC VRSALCQRTL HAYS