PHOH_ECOLI
ID PHOH_ECOLI Reviewed; 354 AA.
AC P0A9K1; P31544;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Protein PhoH;
DE AltName: Full=Phosphate starvation-inducible protein PsiH;
GN Name=phoH; Synonyms=psiH; OrderedLocusNames=b1020, JW1005;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 1-15.
RC STRAIN=K12;
RX PubMed=8444794; DOI=10.1128/jb.175.5.1316-1324.1993;
RA Kim S.-K., Makino K., Amemura M., Shinagawa H., Nakata A.;
RT "Molecular analysis of the phoH gene, belonging to the phosphate regulon in
RT Escherichia coli.";
RL J. Bacteriol. 175:1316-1324(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP CHARACTERIZATION.
RC STRAIN=K12;
RX PubMed=2160940; DOI=10.1128/jb.172.6.3191-3200.1990;
RA Metcalf W.W., Steed P.M., Wanner B.L.;
RT "Identification of phosphate starvation-inducible genes in Escherichia coli
RT K-12 by DNA sequence analysis of psi::lacZ(Mu d1) transcriptional
RT fusions.";
RL J. Bacteriol. 172:3191-3200(1990).
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC -!- INDUCTION: By phosphate starvation.
CC -!- SIMILARITY: Belongs to the PhoH family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D10391; BAA01230.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74105.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35801.1; -; Genomic_DNA.
DR PIR; B47065; B47065.
DR RefSeq; NP_415539.1; NC_000913.3.
DR RefSeq; WP_000258765.1; NZ_CP011343.2.
DR AlphaFoldDB; P0A9K1; -.
DR SMR; P0A9K1; -.
DR BioGRID; 4260054; 9.
DR DIP; DIP-10499N; -.
DR STRING; 511145.b1020; -.
DR PaxDb; P0A9K1; -.
DR PRIDE; P0A9K1; -.
DR EnsemblBacteria; AAC74105; AAC74105; b1020.
DR EnsemblBacteria; BAA35801; BAA35801; BAA35801.
DR GeneID; 948010; -.
DR KEGG; ecj:JW1005; -.
DR KEGG; eco:b1020; -.
DR PATRIC; fig|511145.12.peg.1060; -.
DR EchoBASE; EB1685; -.
DR eggNOG; COG1702; Bacteria.
DR HOGENOM; CLU_051654_4_0_6; -.
DR InParanoid; P0A9K1; -.
DR OMA; EAQNCTY; -.
DR PhylomeDB; P0A9K1; -.
DR BioCyc; EcoCyc:EG11734-MON; -.
DR PRO; PR:P0A9K1; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IDA:EcoCyc.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR Pfam; PF02562; PhoH; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Cytoplasm; Direct protein sequencing; Nucleotide-binding;
KW Reference proteome; Stress response.
FT CHAIN 1..354
FT /note="Protein PhoH"
FT /id="PRO_0000201150"
FT BINDING 173..180
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255"
SQ SEQUENCE 354 AA; 39265 MW; 28E5F229797EB41C CRC64;
MVTSCTGHVL DNQRATTRGV FSSGSHLVTL HFQPHPFFSC VTDAVNGARS RFSAFYPKAN
YGLQGSQPSD VRAHNRAANG ACDEYKQLKV LSMGRQKAVI KARREAKRVL RRDSRSHKQR
EEESVTSLVQ MGGVEAIGMA RDSRDTSPIL ARNEAQLHYL KAIESKQLIF ATGEAGCGKT
WISAAKAAEA LIHKDVDRII VTRPVLQADE DLGFLPGDIA EKFAPYFRPV YDVLVRRLGA
SFMQYCLRPE IGKVEIAPFA YMRGRTFENA VVILDEAQNV TAAQMKMFLT RLGENVTVIV
NGDITQCDLP RGVCSGLSDA LERFEEDEMV GIVRFGKEDC VRSALCQRTL HAYS
