ID   PHOL_MYCLE              Reviewed;         349 AA.
AC   Q49751;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=PhoH-like protein;
GN   OrderedLocusNames=ML0627; ORFNames=B1937_F1_20;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (MAR-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PhoH family. {ECO:0000305}.
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DR   EMBL; U00016; AAA17155.1; -; Genomic_DNA.
DR   EMBL; AL583919; CAC30135.1; -; Genomic_DNA.
DR   PIR; S72587; S72587.
DR   RefSeq; NP_301520.1; NC_002677.1.
DR   AlphaFoldDB; Q49751; -.
DR   SMR; Q49751; -.
DR   STRING; 272631.ML0627; -.
DR   EnsemblBacteria; CAC30135; CAC30135; CAC30135.
DR   KEGG; mle:ML0627; -.
DR   PATRIC; fig|272631.5.peg.1108; -.
DR   Leproma; ML0627; -.
DR   eggNOG; COG1702; Bacteria.
DR   HOGENOM; CLU_051654_0_0_11; -.
DR   OMA; PAQMKMV; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003714; PhoH.
DR   Pfam; PF02562; PhoH; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..349
FT                   /note="PhoH-like protein"
FT                   /id="PRO_0000201157"
FT   BINDING         147..154
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   349 AA;  37701 MW;  26E393F8EED26A7A CRC64;
     MTHHETSAVD ASSASMHVRS TIDVPPDLVV GLLGSADENL RALERMLSAD LHVRGNTVAF
     SGEPADVALA ERAISELVAI VASGHPLTPE VVRHGVAMLV GTGNESPAEV LTLDILLRRG
     KTVRPKTLNQ KRYVDAIDAN TIVFGIGPAG TGKTYLAMAK AVNALQTKQV TRIILTRPAV
     EAGERLGFLP GTLSEKIDPY LRPLYDALYD MMDPELIPKL MSSGVIEVAS LAYMRGRTLN
     DAFIVLDEAQ NTTAEQMKMF LTRLGFGSKV VVTGDVTQID LPGGARSGLR AAVDILEHID
     DIYVAELASV DVVRHRLVSE IVDAYAEYEE HDLGMNRAAR RASGARNRR