ID   PHOL_MYCTO              Reviewed;         352 AA.
AC   P9WIA2; L0TCB4; O05830; P0A5S0;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=PhoH-like protein;
GN   OrderedLocusNames=MT2437;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the PhoH family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK46731.1; -; Genomic_DNA.
DR   PIR; G70586; G70586.
DR   RefSeq; WP_003412235.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WIA2; -.
DR   SMR; P9WIA2; -.
DR   EnsemblBacteria; AAK46731; AAK46731; MT2437.
DR   GeneID; 45426355; -.
DR   KEGG; mtc:MT2437; -.
DR   PATRIC; fig|83331.31.peg.2625; -.
DR   HOGENOM; CLU_051654_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR004087; KH_dom.
DR   InterPro; IPR036612; KH_dom_type_1_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003714; PhoH.
DR   Pfam; PF02562; PhoH; 1.
DR   SMART; SM00322; KH; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54791; SSF54791; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cytoplasm; Nucleotide-binding.
FT   CHAIN           1..352
FT                   /note="PhoH-like protein"
FT                   /id="PRO_0000428042"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         150..157
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   352 AA;  37799 MW;  D34FF896A7678298 CRC64;
     MTSRETRAAD AAGARQADAQ VRSSIDVPPD LVVGLLGSAD ENLRALERTL SADLHVRGNA
     VTLCGEPADV ALAERVISEL IAIVASGQSL TPEVVRHSVA MLVGTGNESP AEVLTLDILS
     RRGKTIRPKT LNQKRYVDAI DANTIVFGIG PAGTGKTYLA MAKAVHALQT KQVTRIILTR
     PAVEAGERLG FLPGTLSEKI DPYLRPLYDA LYDMMDPELI PKLMSAGVIE VAPLAYMRGR
     TLNDAFIVLD EAQNTTAEQM KMFLTRLGFG SKVVVTGDVT QIDLPGGARS GLRAAVDILE
     DIDDIHIAEL TSVDVVRHRL VSEIVDAYAR YEEPGSGLNR AARRASGARG RR