ID   PHON_PROST              Reviewed;         248 AA.
AC   P26975;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Non-specific acid phosphatase;
DE            Short=NSAP;
DE            EC=3.1.3.2;
DE   Flags: Precursor;
GN   Name=phoN;
OS   Providencia stuartii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Providencia.
OX   NCBI_TaxID=588;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PV81;
RA   Riccio M.L., Lombardi G., Chiesurin A., Satta G.;
RL   Submitted (FEB-1992) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC         Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC   -!- SUBCELLULAR LOCATION: Periplasm.
CC   -!- SIMILARITY: Belongs to the class A bacterial acid phosphatase family.
CC       {ECO:0000305}.
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DR   EMBL; X64820; CAA46032.1; -; Genomic_DNA.
DR   PIR; S19888; PAOFCS.
DR   RefSeq; WP_004917790.1; NZ_WLUO01000038.1.
DR   AlphaFoldDB; P26975; -.
DR   SMR; P26975; -.
DR   STRING; 588.BGK56_18655; -.
DR   OrthoDB; 1930882at2; -.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR   CDD; cd03397; PAP2_acid_phosphatase; 1.
DR   InterPro; IPR001011; Acid_Pase_classA_bac.
DR   InterPro; IPR018296; Acid_Pase_classA_bac_CS.
DR   InterPro; IPR036938; P_Acid_Pase_2/haloperoxi_sf.
DR   InterPro; IPR000326; P_Acid_Pase_2/haloperoxidase.
DR   Pfam; PF01569; PAP2; 1.
DR   PIRSF; PIRSF000897; Acid_Ptase_ClsA; 1.
DR   PRINTS; PR00483; BACPHPHTASE.
DR   SMART; SM00014; acidPPc; 1.
DR   SUPFAM; SSF48317; SSF48317; 1.
DR   PROSITE; PS01157; ACID_PHOSPH_CL_A; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Periplasm; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..248
FT                   /note="Non-specific acid phosphatase"
FT                   /id="PRO_0000024000"
SQ   SEQUENCE   248 AA;  27044 MW;  2122A4B95E767CB2 CRC64;
     MKKLLAVFCA GAFVSTSVFA AIPPGNDVTT KPDLYYLKNS QAIDSLALLP PPPEVGSILF
     LNDQAMYEKG RLLRNTERGE QAAKDADLAA GGVANAFSEA FGYPITEKDA PEIHKLLTNM
     IEDAGDLATR SAKEKYMRIR PFAFYGVATC NTKDQDKLSK NGSYPSGHTA IGWASALVLS
     EINPENQDKI LKRGYELGQS RVICGYHWQS DVDAARIVAS GAVATLHSNP EFQKQLQKAK
     DEFAKLKK