ID   PHOSP_DMSVA             Reviewed;         313 AA.
AC   A7WNB2;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   29-SEP-2021, entry version 22.
DE   RecName: Full=Phosphoprotein;
DE            Short=P protein;
GN   Name=P;
OS   Drosophila melanogaster sigma virus (isolate Drosophila/USA/AP30/2005)
OS   (DMelSV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Alpharhabdovirinae;
OC   Sigmavirus.
OX   NCBI_TaxID=666363;
OH   NCBI_TaxID=7227; Drosophila melanogaster (Fruit fly).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=AP30;
RX   PubMed=17725574; DOI=10.1111/j.1365-294x.2007.03460.x;
RA   Carpenter J.A., Obbard D.J., Maside X., Jiggins F.M.;
RT   "The recent spread of a vertically transmitted virus through populations of
RT   Drosophila melanogaster.";
RL   Mol. Ecol. 16:3947-3954(2007).
CC   -!- FUNCTION: Essential component of the RNA polymerase transcription and
CC       replication complex. Binds the viral ribonucleocapsid and positions the
CC       L polymerase on the template. May act as a chaperone for newly
CC       synthesized free N protein, so-called N(0). Plays a role in virion
CC       assembly. {ECO:0000250|UniProtKB:P03520}.
CC   -!- SUBUNIT: Homotrimer. This trimer is stabilized by binding to the L
CC       protein. Binds N(0), and N in ribonucleocapsid.
CC       {ECO:0000250|UniProtKB:P03520}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03520}. Host
CC       cytoplasm {ECO:0000250|UniProtKB:P03520}.
CC   -!- PTM: Phosphorylated by host kinases. Phosphorylation play an important
CC       role in facilitating trimerization and possibly P-L complex formation.
CC       {ECO:0000250|UniProtKB:P03520}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM689309; CAM82925.3; -; Genomic_RNA.
DR   RefSeq; YP_003126909.1; NC_013135.1.
DR   GeneID; 8363510; -.
DR   KEGG; vg:8363510; -.
DR   Proteomes; UP000029768; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019083; P:viral transcription; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Chaperone; Host cytoplasm; Phosphoprotein; Reference proteome;
KW   Viral RNA replication; Viral transcription; Virion.
FT   CHAIN           1..313
FT                   /note="Phosphoprotein"
FT                   /id="PRO_0000432068"
FT   REGION          189..208
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   313 AA;  35251 MW;  B0F246465D79F4EF CRC64;
     MNLTQEDEQR LALLRERAAA WDHKNALGEF ESNAELDVYN EGIAYPPSID EMEVGEGRPT
     LDKILESSIG SDSLPNLEDG PPDQEAAYHE GEMYSTMMTS YMDQDNENMD LSAGPTCSTP
     QPITGIHHKE TINGRVTQMV YIGETSDMAL INRLQDEFDV LYNTYPNRNK QGEIVHLIVM
     WSTPLKPSTR YSLSPAQPPG KKRKIVQHSS NPEPEIVFVP EPTSSEQSLP ERQIKAYLQR
     GIELKGKSAE VPNFKITNET LGFSDANLKL LYPDTSLYPD NPVFILEDVF ASTRQLNKIK
     VNYQLYDPVL PSI