ID   PHOSP_NDVB1             Reviewed;         395 AA.
AC   Q9DLD6;
DT   19-JAN-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   02-JUN-2021, entry version 54.
DE   RecName: Full=Phosphoprotein;
DE            Short=Protein P;
GN   Name=P;
OS   Newcastle disease virus (strain Chicken/United States/B1/48) (NDV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Avulavirinae;
OC   Orthoavulavirus; Avian orthoavulavirus 1.
OX   NCBI_TaxID=652953;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RA   Sellers H.S., Seal B.S.;
RT   "Complete sequence for the B1 strain of Newcastle disease virus.";
RL   Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the RNA polymerase transcription and
CC       replication complex. Binds the viral ribonucleocapsid and positions the
CC       L polymerase on the template (By similarity). {ECO:0000250}.
CC   -!- FUNCTION: Acts as a chaperone for newly synthesized free N protein, so-
CC       called N(0). Stabilizes the L protein upon binding it (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homotetramer. Binds to the L protein, N(0) and to the C-
CC       terminal domain of N in ribonucleocapsid (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host cytoplasm.
CC   -!- DOMAIN: The L protein binding domain is necessary for viral RNA
CC       synthesis, whereas the N(0) binding domain is not. Two separate regions
CC       are required for binding to the nucleocapsid (By similarity).
CC       {ECO:0000250}.
CC   -!- RNA EDITING: Modified_positions=136 {ECO:0000250}; Note=Partially
CC       edited. RNA editing at this position consists of an insertion of one or
CC       two guanine nucleotides. The sequence displayed here is the P protein,
CC       derived from the unedited RNA. The edited RNA gives rise to the V
CC       protein (+1G) (AC P0C765), and the W protein (+2G) (AC P0C766) (By
CC       similarity). {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the rubulavirus/avulavirus P protein family.
CC       {ECO:0000305}.
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DR   EMBL; AF309418; AAG36983.1; -; Genomic_RNA.
DR   RefSeq; NP_071467.1; NC_002617.1.
DR   SMR; Q9DLD6; -.
DR   Proteomes; UP000002328; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004897; P/V_Pprotein_paramyxoviral.
DR   InterPro; IPR025909; Soyouz_module.
DR   Pfam; PF03210; Paramyx_P_V_C; 1.
DR   Pfam; PF14313; Soyouz_module; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Phosphoprotein; Reference proteome; RNA editing;
KW   Viral RNA replication.
FT   CHAIN           1..395
FT                   /note="Phosphoprotein"
FT                   /id="PRO_0000390626"
FT   REGION          46..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          127..181
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          193..217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..105
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        193..214
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   395 AA;  42292 MW;  61C528061C07B7CA CRC64;
     MATFTDAEID ELFETSGTVI DNIITAQGKP AETVGRSAIP QGKTKVLSAA WEKHGSIQPP
     ASQDNPDRQD RSDKQPSTPE QTTPHDSPPA TSADQPPTQA TDEAVDTQLR TGASNSLLLM
     LDKLSNKSSN AKKGPWSSPQ EGNHQRPTQQ QGSQPSRGNS QERPQNQVKA APGNQGTDVN
     TAYHGQWEES QLSAGATPHG LRSKQSQNNT PVSADHFHPP VDFVQAMMSI MEGISQRVSK
     VAYQVDLVFK QTSSIPMMGS EIQQLKTFVA VMEANLGMMK ILDPGCANIS SLSDLRAVAR
     SHPVLVSGPG DPSPYVIQGG EMALNKLSQP VPHPSELIKP ATACGPDIGV ERDTVRALIM
     SRPMHPSSSA KLLSKLDAAG SIEEIRKIKR LALNG