ID   PHOSP_NDVU2             Reviewed;         395 AA.
AC   Q06427;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 2.
DT   23-FEB-2022, entry version 78.
DE   RecName: Full=Phosphoprotein;
DE            Short=Protein P;
GN   Name=P/V;
OS   Newcastle disease virus (strain Ulster/2C) (NDV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Avulavirinae;
OC   Orthoavulavirus; Avian orthoavulavirus 1.
OX   NCBI_TaxID=36411;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA / MRNA], AND RNA EDITING.
RX   PubMed=8277263; DOI=10.1099/0022-1317-74-12-2539;
RA   Steward M., Vipond I.B., Millar N.S., Emmerson P.T.;
RT   "RNA editing in Newcastle disease virus.";
RL   J. Gen. Virol. 74:2539-2547(1993).
CC   -!- FUNCTION: Essential component of the RNA polymerase and the nascent
CC       chain assembly complex. Also required during RNA synthesis.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative initiation; Named isoforms=3;
CC       Name=Long;
CC         IsoId=Q06427-1; Sequence=Displayed;
CC       Name=38 kDa; Synonyms=Non-structural protein C 38 kDa;
CC         IsoId=Q06427-2; Sequence=VSP_018926, VSP_018927;
CC       Name=29 kDa; Synonyms=Non-structural protein C 29 kDa;
CC         IsoId=Q06427-3; Sequence=VSP_018928;
CC   -!- RNA EDITING: Modified_positions=135 {ECO:0000269|PubMed:8277263};
CC       Note=Partially edited. RNA editing at this position consists of an
CC       insertion of one guanine nucleotide. The sequence displayed here is the
CC       P protein, derived from the unedited RNA. The edited RNA version gives
CC       rise to the V protein (AC Q06428).;
CC   -!- SIMILARITY: Belongs to the rubulavirus/avulavirus P protein family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z26249; CAA81208.1; -; Genomic_RNA.
DR   PIR; JQ2392; JQ2392.
DR   SMR; Q06427; -.
DR   InterPro; IPR004897; P/V_Pprotein_paramyxoviral.
DR   InterPro; IPR025909; Soyouz_module.
DR   Pfam; PF03210; Paramyx_P_V_C; 1.
DR   Pfam; PF14313; Soyouz_module; 1.
PE   3: Inferred from homology;
KW   Alternative initiation; Phosphoprotein; RNA editing; Viral RNA replication.
FT   CHAIN           1..395
FT                   /note="Phosphoprotein"
FT                   /id="PRO_0000039387"
FT   REGION          34..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..179
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..65
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        76..104
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        192..213
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         1..119
FT                   /note="Missing (in isoform 29 kDa)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018928"
FT   VAR_SEQ         1..81
FT                   /note="Missing (in isoform 38 kDa)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018926"
FT   VAR_SEQ         82
FT                   /note="V -> M (in isoform 38 kDa)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_018927"
SQ   SEQUENCE   395 AA;  42237 MW;  019CA5763471093E CRC64;
     MATFTDAEID ELFETSGTVI DSIITAQGKP VETVGRSAIP RGKTKALSSA WEKHGSVQSP
     ASQDTPDRQD RSDKQLSTPE QVTPHDSPPA TSTDQPPTQA ADEAGDTQLK TGASNSLLSM
     LDKLSNKSSN AKKGPWSSPQ EGHHQRPTQQ QGSQPSRGNS QERPQNQVKA APGSQGTDAN
     IAYHGQWEES QLSAGATHHA LRSGQSQDNT PAPVDHVQLP VDFVQAMMSM MEAISQRVSK
     VDYQLDLVLK QTSSIPMMRS EIQQLKTSVA VMEANLGMMK ILDPGCANVS SLSDLRAVAR
     SHPVLVSGPG DPSPYVTQGG EMALNKLSQP VQHPSELIKP AMVSGPDIGV EKDTVRALIM
     SRPMHPSSSA KLLSKLDAAG SIEEIRKIKR LALNG