ID   PHOSP_PI4HB             Reviewed;         399 AA.
AC   P21738;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   02-JUN-2021, entry version 72.
DE   RecName: Full=Phosphoprotein;
DE            Short=Protein P;
GN   Name=P/V;
OS   Human parainfluenza 4b virus (strain 68-333) (HPIV-4b).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Paramyxoviridae; Rubulavirinae;
OC   Orthorubulavirus; Human orthorubulavirus 4.
OX   NCBI_TaxID=11227;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA], AND RNA EDITING.
RX   PubMed=2167560; DOI=10.1016/0042-6822(90)90413-l;
RA   Kondo K., Bando H., Tsurudome M., Kawano M., Nishio M., Ito Y.;
RT   "Sequence analysis of the phosphoprotein (P) genes of human parainfluenza
RT   type 4A and 4B viruses and RNA editing at transcript of the P genes: the
RT   number of G residues added is imprecise.";
RL   Virology 178:321-326(1990).
CC   -!- FUNCTION: Essential component of the RNA polymerase and the nascent
CC       chain assembly complex. Also required during RNA synthesis.
CC   -!- RNA EDITING: Modified_positions=153 {ECO:0000269|PubMed:2167560};
CC       Note=Partially edited. RNA editing at this position consists of an
CC       insertion of two guanine nucleotides. The sequence displayed here is
CC       the P protein, derived from the edited RNA. The unedited RNA version
CC       gives rise to the V protein (AC P21740).;
CC   -!- SIMILARITY: Belongs to the rubulavirus/avulavirus P protein family.
CC       {ECO:0000305}.
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DR   EMBL; M55976; AAA46806.1; -; Genomic_RNA.
DR   PIR; C43685; C43685.
DR   PDB; 4KYD; X-ray; 2.21 A; A/B=351-399.
DR   PDB; 4KYE; X-ray; 2.60 A; A=351-399.
DR   PDBsum; 4KYD; -.
DR   PDBsum; 4KYE; -.
DR   SMR; P21738; -.
DR   PRIDE; P21738; -.
DR   InterPro; IPR004897; P/V_Pprotein_paramyxoviral.
DR   Pfam; PF03210; Paramyx_P_V_C; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Phosphoprotein; RNA editing; Viral RNA replication.
FT   CHAIN           1..399
FT                   /note="Phosphoprotein"
FT                   /id="PRO_0000142708"
FT   REGION          28..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..149
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        83..115
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   HELIX           351..365
FT                   /evidence="ECO:0007829|PDB:4KYD"
FT   HELIX           369..378
FT                   /evidence="ECO:0007829|PDB:4KYD"
SQ   SEQUENCE   399 AA;  44135 MW;  6FC51941A849B3BF CRC64;
     MSFEISVEEI DELIETGNLN IDYALKELGA TSQPPPNRPL SQISKTEENN DETRTSKNSA
     SAEAPAHASS PLRSHNEESE PGKQSSDGFS MISNRPQTGM LLMGSDTQSP SPSKTYQGLI
     LDAKKRALNE PRRNQKTTNE HGNTNDTWIF KRGGNIATKK EAWVTQNQRS KIQSSFQDIE
     ESTRFHGSME EPQYQSGAIH VAHQSNQLPP SKNVHVEDVP KFANYALEIL DAIKALEVRL
     DRIEGKVDKI MLTQNTIQQT KNDTQQIKGS LATIEGLITT MKIMDPGVPS KVSLRSLNKG
     PEQVPIIVTG TGDVSKFVDQ DNTITLDPLA RPILSGTKQI TDERRAGVRI DALKITVSEM
     IRDLFGDCDK SRKLLESINM ATTEQDINSI KTNALRSIT