位置:首页 > 蛋白库 > PHOSP_TIBVC
PHOSP_TIBVC
ID   PHOSP_TIBVC             Reviewed;         308 AA.
AC   D8V071;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2010, sequence version 1.
DT   23-FEB-2022, entry version 21.
DE   RecName: Full=Phosphoprotein;
DE            Short=P protein;
GN   Name=P;
OS   Tibrogargan virus (strain CS132) (TIBV).
OC   Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina;
OC   Monjiviricetes; Mononegavirales; Rhabdoviridae; Alpharhabdovirinae;
OC   Tibrovirus.
OX   NCBI_TaxID=1559361;
OH   NCBI_TaxID=9913; Bos taurus (Bovine).
OH   NCBI_TaxID=469753; Culicoides brevitarsis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RC   STRAIN=CS132;
RX   PubMed=21593274; DOI=10.1099/vir.0.026120-0;
RA   Gubala A., Davis S., Weir R., Melville L., Cowled C., Boyle D.;
RT   "Tibrogargan and Coastal Plains rhabdoviruses: genomic characterization,
RT   evolution of novel genes and seroprevalence in Australian livestock.";
RL   J. Gen. Virol. 92:2160-2170(2011).
CC   -!- FUNCTION: Essential component of the RNA polymerase transcription and
CC       replication complex. Binds the viral ribonucleocapsid and positions the
CC       L polymerase on the template. May act as a chaperone for newly
CC       synthesized free N protein, so-called N(0). Plays a role in virion
CC       assembly. {ECO:0000250|UniProtKB:P03520}.
CC   -!- SUBUNIT: Homotrimer. This trimer is stabilized by binding to the L
CC       protein. Binds N(0), and N in ribonucleocapsid.
CC       {ECO:0000250|UniProtKB:P03520}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:P03520}. Host
CC       cytoplasm {ECO:0000250|UniProtKB:P03520}.
CC   -!- PTM: Phosphorylated by host kinases. Phosphorylation play an important
CC       role in facilitating trimerization and possibly P-L complex formation.
CC       {ECO:0000250|UniProtKB:P03520}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GQ294472; ADG86348.1; -; Viral_cRNA.
DR   RefSeq; YP_007641369.1; NC_020804.1.
DR   GeneID; 14857899; -.
DR   KEGG; vg:14857899; -.
DR   Proteomes; UP000029770; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019083; P:viral transcription; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Chaperone; Host cytoplasm; Phosphoprotein; Reference proteome;
KW   Viral RNA replication; Viral transcription; Virion.
FT   CHAIN           1..308
FT                   /note="Phosphoprotein"
FT                   /id="PRO_0000432070"
SQ   SEQUENCE   308 AA;  35908 MW;  C812F3A1C9732D7A CRC64;
     MKRHRISIPY VTDQVLRNTS DVVDPNDTVD QLISDDVVNP KQDLKEFLDS RELNYRTRAS
     LASSYDDDDW ADSIVDLSQR PHNKMEESSL HDDKAIKQAT QLNTDYNQLR SPNANSIGGQ
     SVIKDVSSER KPPVNQIPED QQIYPSQMYP LLEVPESYHS LIPKLQFFFK YYGLYEDSDY
     VVDKDNQGYY FYPTKKWTTR DQKELMDNIS KGVDHDDNLL DLEEKTSDNL FEENLNVHQL
     VDFVTKGFYV EKRNIKGKYY FDINNPSLNI NKIANVDCQD KILSAKEKID MIFKASGIYR
     AMKLKAKW
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024