ID   PHOT_LISMO              Reviewed;         253 AA.
AC   P58724;
DT   31-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   31-JAN-2002, sequence version 1.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=Blue-light photoreceptor;
DE   AltName: Full=Phototropin homolog;
GN   OrderedLocusNames=lmo0799;
OS   Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=169963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-679 / EGD-e;
RX   PubMed=11679669; DOI=10.1126/science.1063447;
RA   Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F.,
RA   Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A.,
RA   Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E.,
RA   Dominguez-Bernal G., Duchaud E., Durant L., Dussurget O., Entian K.-D.,
RA   Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W.,
RA   Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U.,
RA   Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A.,
RA   Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B.,
RA   Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N.,
RA   Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P.;
RT   "Comparative genomics of Listeria species.";
RL   Science 294:849-852(2001).
CC   -!- FUNCTION: Exhibits the same spectroscopical features and blue-light
CC       induced photochemistry as plants phototropins, with the reversible
CC       formation of a blue-shifted photoproduct, assigned to an FMN-cysteine
CC       thiol adduct. Positive regulator in the activation of the general
CC       stress transcription factor sigma-B (By similarity). {ECO:0000250}.
CC   -!- PTM: FMN binds covalently to cysteine after exposure to blue light and
CC       this bond is spontaneously broken in the dark. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL591976; CAC98877.1; -; Genomic_DNA.
DR   PIR; AG1174; AG1174.
DR   RefSeq; NP_464326.1; NC_003210.1.
DR   RefSeq; WP_003723977.1; NZ_CP023861.1.
DR   AlphaFoldDB; P58724; -.
DR   SMR; P58724; -.
DR   STRING; 169963.lmo0799; -.
DR   PaxDb; P58724; -.
DR   DNASU; 985420; -.
DR   EnsemblBacteria; CAC98877; CAC98877; CAC98877.
DR   GeneID; 985420; -.
DR   KEGG; lmo:lmo0799; -.
DR   PATRIC; fig|169963.11.peg.822; -.
DR   eggNOG; COG1366; Bacteria.
DR   HOGENOM; CLU_080905_0_0_9; -.
DR   OMA; FWNELNI; -.
DR   PhylomeDB; P58724; -.
DR   BioCyc; LMON169963:LMO0799-MON; -.
DR   Proteomes; UP000000817; Chromosome.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   Pfam; PF13426; PAS_9; 1.
DR   Pfam; PF01740; STAS; 1.
DR   SMART; SM00086; PAC; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Chromophore; Flavoprotein; FMN; Photoreceptor protein; Receptor;
KW   Reference proteome; Sensory transduction; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..253
FT                   /note="Blue-light photoreceptor"
FT                   /id="PRO_0000172006"
FT   DOMAIN          6..79
FT                   /note="PAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT   DOMAIN          80..133
FT                   /note="PAC"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00141"
FT   DOMAIN          142..253
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
FT   MOD_RES         56
FT                   /note="S-4a-FMN cysteine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   253 AA;  28817 MW;  43BDC7D7348DCC66 CRC64;
     MTAYPQFDVI LKALNLSSVG VIITDPEQKD NPIIFVNTGF ENITGYAKEE ALGSNCHFLQ
     GDDTDKEEVA KIRHAINEKS TANVLLKNYR KDGTSFMNEL TIEPIYDDHE HLYFVGIQKD
     VTTEHDYQLE LEKSLTEIEK LSTPIVPIKE NICVLPLIGS LTHDRFQHMS EYVSEYMDHG
     KEDYLIMDLS GLAEFNEDAV MNLVKFHGFM KLTGVELIIT GISPKFAMTL IRYEENLASL
     TTYSTIKEAL QFY