ID   PHOU1_THEMA             Reviewed;         232 AA.
AC   Q9X0Y7;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Phosphate-specific transport system accessory protein PhoU homolog 1;
DE            Short=Pst system accessory protein PhoU homolog 1;
GN   Name=phoU1; OrderedLocusNames=TM_1260;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- FUNCTION: Plays a role in the regulation of phosphate uptake.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PhoU family. {ECO:0000305}.
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DR   EMBL; AE000512; AAD36334.1; -; Genomic_DNA.
DR   PIR; G72275; G72275.
DR   RefSeq; NP_229065.1; NC_000853.1.
DR   RefSeq; WP_004080001.1; NZ_CP011107.1.
DR   AlphaFoldDB; Q9X0Y7; -.
DR   SMR; Q9X0Y7; -.
DR   STRING; 243274.THEMA_08035; -.
DR   DNASU; 898223; -.
DR   EnsemblBacteria; AAD36334; AAD36334; TM_1260.
DR   KEGG; tma:TM1260; -.
DR   KEGG; tmw:THMA_1285; -.
DR   PATRIC; fig|243274.18.peg.1554; -.
DR   eggNOG; COG0704; Bacteria.
DR   InParanoid; Q9X0Y7; -.
DR   OMA; WKHGIET; -.
DR   OrthoDB; 1648549at2; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IEA:InterPro.
DR   GO; GO:0045936; P:negative regulation of phosphate metabolic process; ISS:UniProtKB.
DR   GO; GO:2000186; P:negative regulation of phosphate transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.58.220; -; 1.
DR   InterPro; IPR028366; P_transport_PhoU.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   PANTHER; PTHR42930; PTHR42930; 1.
DR   Pfam; PF01895; PhoU; 2.
DR   PIRSF; PIRSF003107; PhoU; 1.
DR   TIGRFAMs; TIGR02135; phoU_full; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Phosphate transport; Reference proteome; Transport.
FT   CHAIN           1..232
FT                   /note="Phosphate-specific transport system accessory
FT                   protein PhoU homolog 1"
FT                   /id="PRO_0000155182"
SQ   SEQUENCE   232 AA;  26937 MW;  DB9F6D49363CE6C3 CRC64;
     MVDHVHFERE LTLLKSDVSK MLFLVSESLN DAIESLETMN ETLARKVLES DDMIDELNRE
     IEEKAYQIIA RYNPILKQLR YIITILKFSN DLERIGDLSC NIAEKCLFLS EEKIKFEMLK
     ELKDMFGSTL KVVQDAFKAF VEEDVDLAFR LWKFDDVIDE MEKKIRRIVV ERIREGNISA
     ELALVYILIA RDLERVGDHA NNLCEEVIYI ETGKNMKEFL RGVESGSEGA DS