PHOU2_METTH
ID PHOU2_METTH Reviewed; 217 AA.
AC O27765;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 106.
DE RecName: Full=Phosphate-specific transport system accessory protein PhoU homolog 2;
DE Short=Pst system accessory protein PhoU homolog 2;
GN OrderedLocusNames=MTH_1732;
OS Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS 10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX NCBI_TaxID=187420;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA Reeve J.N.;
RT "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT functional analysis and comparative genomics.";
RL J. Bacteriol. 179:7135-7155(1997).
CC -!- FUNCTION: Plays a role in the regulation of phosphate uptake.
CC {ECO:0000250}.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PhoU family. {ECO:0000305}.
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DR EMBL; AE000666; AAB86202.1; -; Genomic_DNA.
DR PIR; F69098; F69098.
DR AlphaFoldDB; O27765; -.
DR SMR; O27765; -.
DR STRING; 187420.MTH_1732; -.
DR EnsemblBacteria; AAB86202; AAB86202; MTH_1732.
DR KEGG; mth:MTH_1732; -.
DR PATRIC; fig|187420.15.peg.1691; -.
DR HOGENOM; CLU_078518_3_0_2; -.
DR OMA; RIGNHAS; -.
DR Proteomes; UP000005223; Chromosome.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR GO; GO:0030643; P:cellular phosphate ion homeostasis; IEA:InterPro.
DR GO; GO:0045936; P:negative regulation of phosphate metabolic process; ISS:UniProtKB.
DR GO; GO:2000186; P:negative regulation of phosphate transmembrane transport; ISS:UniProtKB.
DR GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.220; -; 1.
DR InterPro; IPR028366; P_transport_PhoU.
DR InterPro; IPR038078; PhoU-like_sf.
DR InterPro; IPR026022; PhoU_dom.
DR PANTHER; PTHR42930; PTHR42930; 1.
DR Pfam; PF01895; PhoU; 1.
DR PIRSF; PIRSF003107; PhoU; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Phosphate transport; Reference proteome; Transport.
FT CHAIN 1..217
FT /note="Phosphate-specific transport system accessory
FT protein PhoU homolog 2"
FT /id="PRO_0000155190"
SQ SEQUENCE 217 AA; 24914 MW; DF461E0567632EC6 CRC64;
MWKLIGALLE SRLSNVLDET VRYGNETSER VGRTVSSYIK GDEETARELI ETTAAVNEKS
YRIEDECLKI LGLHQPVAKD LRLASSIMRS AIELERINIL LAYIARYAID GRDRTPPHIE
FMSQTVQDMI NDALGALMNR DIQLLKRSTR NYIQLQDLYN QLQESNRDFS ESGNLMLVAR
NLLSMGHHVM GMDDRIAYLI VGKRVIHHKV FYSVLMK