ID   PHOU_BORBU              Reviewed;         223 AA.
AC   O51071;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Phosphate-specific transport system accessory protein PhoU homolog;
DE            Short=Pst system accessory protein PhoU homolog;
GN   Name=phoU; OrderedLocusNames=BB_0042;
OS   Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)
OS   (Borrelia burgdorferi).
OC   Bacteria; Spirochaetes; Spirochaetales; Borreliaceae; Borreliella.
OX   NCBI_TaxID=224326;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35210 / DSM 4680 / CIP 102532 / B31;
RX   PubMed=9403685; DOI=10.1038/37551;
RA   Fraser C.M., Casjens S., Huang W.M., Sutton G.G., Clayton R.A.,
RA   Lathigra R., White O., Ketchum K.A., Dodson R.J., Hickey E.K., Gwinn M.L.,
RA   Dougherty B.A., Tomb J.-F., Fleischmann R.D., Richardson D.L.,
RA   Peterson J.D., Kerlavage A.R., Quackenbush J., Salzberg S.L., Hanson M.,
RA   van Vugt R., Palmer N., Adams M.D., Gocayne J.D., Weidman J.F.,
RA   Utterback T.R., Watthey L., McDonald L.A., Artiach P., Bowman C.,
RA   Garland S.A., Fujii C., Cotton M.D., Horst K., Roberts K.M., Hatch B.,
RA   Smith H.O., Venter J.C.;
RT   "Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi.";
RL   Nature 390:580-586(1997).
CC   -!- FUNCTION: Plays a role in the regulation of phosphate uptake.
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the PhoU family. {ECO:0000305}.
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DR   EMBL; AE000783; AAC66437.1; -; Genomic_DNA.
DR   PIR; B70105; B70105.
DR   RefSeq; NP_212176.1; NC_001318.1.
DR   RefSeq; WP_002556647.1; NC_001318.1.
DR   AlphaFoldDB; O51071; -.
DR   SMR; O51071; -.
DR   STRING; 224326.BB_0042; -.
DR   PRIDE; O51071; -.
DR   EnsemblBacteria; AAC66437; AAC66437; BB_0042.
DR   GeneID; 56568174; -.
DR   KEGG; bbu:BB_0042; -.
DR   PATRIC; fig|224326.49.peg.440; -.
DR   HOGENOM; CLU_078518_2_0_12; -.
DR   OMA; WKHGIET; -.
DR   Proteomes; UP000001807; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.
DR   GO; GO:0030643; P:cellular phosphate ion homeostasis; IEA:InterPro.
DR   GO; GO:0045936; P:negative regulation of phosphate metabolic process; ISS:UniProtKB.
DR   GO; GO:2000186; P:negative regulation of phosphate transmembrane transport; ISS:UniProtKB.
DR   GO; GO:0006817; P:phosphate ion transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.58.220; -; 2.
DR   InterPro; IPR028366; P_transport_PhoU.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   PANTHER; PTHR42930; PTHR42930; 1.
DR   Pfam; PF01895; PhoU; 2.
DR   PIRSF; PIRSF003107; PhoU; 1.
DR   TIGRFAMs; TIGR02135; phoU_full; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Phosphate transport; Reference proteome; Transport.
FT   CHAIN           1..223
FT                   /note="Phosphate-specific transport system accessory
FT                   protein PhoU homolog"
FT                   /id="PRO_0000155164"
SQ   SEQUENCE   223 AA;  25980 MW;  B1FE3BA803EDEA64 CRC64;
     MIRRKLTKQL EIIKDYLWDM KECVLKIIDD SLIALESKDK NLAKKIINED EKIIDDYQYD
     IEDLCGRIIA TEHPVATELR EILAIIKIIS SLERIADHAT KIVKVVLLLE SDLDDFDFLN
     LYFKPLREMA DTAKEMLSDI FDAYFDGDFT KILKIVKYDN IIDKLFSKQK SIVIDAMKKN
     PENLDYLLNI LFLNSFLERV GDHVATIGEL LYFIRIGEKV NLT