ID   PHR2_ARATH              Reviewed;         447 AA.
AC   Q8LB72; O22253;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Blue-light photoreceptor PHR2;
GN   Name=PHR2; OrderedLocusNames=At2g47590; ORFNames=T30B22.11;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia;
RA   Ahmad M., Jarillo J.A., Cashmore A.R.;
RT   "PHR2: a novel Arabidopsis gene related to the blue-light
RT   photoreceptor/photolyase family.";
RL   (er) Plant Gene Register PGR98-096(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC       Note=Binds 1 FAD per subunit. {ECO:0000250};
CC   -!- SIMILARITY: Belongs to the DNA photolyase class-1 family.
CC       {ECO:0000305}.
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DR   EMBL; AF053366; AAC26199.1; -; mRNA.
DR   EMBL; AC002535; AAC62851.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC10862.1; -; Genomic_DNA.
DR   EMBL; AY087383; AAM64933.1; -; mRNA.
DR   PIR; T00425; T00425.
DR   RefSeq; NP_182281.1; NM_130327.4.
DR   AlphaFoldDB; Q8LB72; -.
DR   SMR; Q8LB72; -.
DR   BioGRID; 4707; 4.
DR   STRING; 3702.AT2G47590.1; -.
DR   PaxDb; Q8LB72; -.
DR   PRIDE; Q8LB72; -.
DR   ProteomicsDB; 235106; -.
DR   EnsemblPlants; AT2G47590.1; AT2G47590.1; AT2G47590.
DR   GeneID; 819372; -.
DR   Gramene; AT2G47590.1; AT2G47590.1; AT2G47590.
DR   KEGG; ath:AT2G47590; -.
DR   Araport; AT2G47590; -.
DR   TAIR; locus:2061961; AT2G47590.
DR   eggNOG; KOG0133; Eukaryota.
DR   HOGENOM; CLU_010348_0_0_1; -.
DR   InParanoid; Q8LB72; -.
DR   OMA; VMKDEGL; -.
DR   OrthoDB; 378952at2759; -.
DR   PhylomeDB; Q8LB72; -.
DR   PRO; PR:Q8LB72; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q8LB72; baseline and differential.
DR   Genevisible; Q8LB72; AT.
DR   GO; GO:0003904; F:deoxyribodipyrimidine photo-lyase activity; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IBA:GO_Central.
DR   GO; GO:0071949; F:FAD binding; IBA:GO_Central.
DR   GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0000719; P:photoreactive repair; IBA:GO_Central.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR036134; Crypto/Photolyase_FAD-like_sf.
DR   InterPro; IPR036155; Crypto/Photolyase_N_sf.
DR   InterPro; IPR002081; Cryptochrome/DNA_photolyase_1.
DR   InterPro; IPR006050; DNA_photolyase_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR11455; PTHR11455; 1.
DR   Pfam; PF00875; DNA_photolyase; 1.
DR   SUPFAM; SSF48173; SSF48173; 1.
DR   SUPFAM; SSF52425; SSF52425; 1.
DR   PROSITE; PS51645; PHR_CRY_ALPHA_BETA; 1.
PE   2: Evidence at transcript level;
KW   Chromophore; FAD; Flavoprotein; Photoreceptor protein; Receptor;
KW   Reference proteome; Sensory transduction.
FT   CHAIN           1..447
FT                   /note="Blue-light photoreceptor PHR2"
FT                   /id="PRO_0000253763"
FT   DOMAIN          115..249
FT                   /note="Photolyase/cryptochrome alpha/beta"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   447 AA;  48878 MW;  29194B6DBDF6DA7C CRC64;
     MDSSNVEENL NPETKSAEEQ NPLAIFHSSL PIASLSLTLF PSSTQFLKLF AHHPNKVKIP
     TQASSLTHLS LSSVSPFPSS RISFKSTIAA NPLQSPLSIV PRRPVDPSSA AALRRAAVVW
     FRNDLRVHDN ECLNSANDEC VSVLPVYCFD PRDYGKSSSG FDKTGPFRAQ FLIESVSELR
     KNLQARGSNL VVRVGKPEAV LVELAKEIGA DAVYAHREVS HDEVKAEGKI ETAMKEEGVE
     VKYFWGSTLY HLDDLPFKIE DLPSNYGAFK DKVQKLEIRK TIAALDQLKS LPSRGDVELG
     DIPSLLDLGI SPTPRTSQEG KPTMVGGETE ALTRLKSFAA DCQARLSKGN QKGGNNSVFG
     ANFSCKISPW LAMGSISPRS MFDELKKTIS ASTTSTTPRN GPGDTGLNWL MYELLWRDFF
     RFITKKYSSA KTQVEAGPAT ACTGAFA