ID   PHS1_GLOVI              Reviewed;         116 AA.
AC   Q7NM43;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase 1;
DE            Short=PHS 1;
DE            EC=4.2.1.96;
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase 1;
DE   AltName: Full=Pterin carbinolamine dehydratase 1;
DE            Short=PCD 1;
GN   OrderedLocusNames=gll0926;
OS   Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC   Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae;
OC   Gloeobacter.
OX   NCBI_TaxID=251221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29082 / PCC 7421;
RX   PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA   Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA   Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA   Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT   cyanobacterium that lacks thylakoids.";
RL   DNA Res. 10:137-145(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin =
CC         (6R)-L-erythro-6,7-dihydrobiopterin + H2O; Xref=Rhea:RHEA:11920,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15642, ChEBI:CHEBI:43120; EC=4.2.1.96;
CC   -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine dehydratase
CC       family. {ECO:0000305}.
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DR   EMBL; BA000045; BAC88867.1; -; Genomic_DNA.
DR   RefSeq; NP_923872.1; NC_005125.1.
DR   RefSeq; WP_011140928.1; NC_005125.1.
DR   AlphaFoldDB; Q7NM43; -.
DR   SMR; Q7NM43; -.
DR   STRING; 251221.35211489; -.
DR   EnsemblBacteria; BAC88867; BAC88867; BAC88867.
DR   KEGG; gvi:gll0926; -.
DR   PATRIC; fig|251221.4.peg.945; -.
DR   eggNOG; COG2154; Bacteria.
DR   HOGENOM; CLU_081974_2_2_3; -.
DR   InParanoid; Q7NM43; -.
DR   OMA; FHHPGIL; -.
DR   OrthoDB; 1862336at2; -.
DR   PhylomeDB; Q7NM43; -.
DR   Proteomes; UP000000557; Chromosome.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1360.20; -; 1.
DR   HAMAP; MF_00434; Pterin_4_alpha; 1.
DR   InterPro; IPR036428; PCD_sf.
DR   InterPro; IPR001533; Pterin_deHydtase.
DR   Pfam; PF01329; Pterin_4a; 1.
DR   SUPFAM; SSF55248; SSF55248; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome.
FT   CHAIN           1..116
FT                   /note="Putative pterin-4-alpha-carbinolamine dehydratase 1"
FT                   /id="PRO_0000063081"
SQ   SEQUENCE   116 AA;  12922 MW;  FBE74B18B3D0701E CRC64;
     MNLTEQRCTA CRPDAPRVGA AEIAELHPQI PAWRIVEIEG TPRLERQFRL RDFREAIAFT
     VRVGEEAEAE GHHPALLTEW GSVKVSWWTH AIAGLHRNDF VMAAKTDAIA AQVGAV