ID   PHS2_GLOVI              Reviewed;          92 AA.
AC   Q7NK35;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2003, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Putative pterin-4-alpha-carbinolamine dehydratase 2;
DE            Short=PHS 2;
DE            EC=4.2.1.96;
DE   AltName: Full=4-alpha-hydroxy-tetrahydropterin dehydratase 2;
DE   AltName: Full=Pterin carbinolamine dehydratase 2;
DE            Short=PCD 2;
GN   OrderedLocusNames=gsl1645;
OS   Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC   Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae;
OC   Gloeobacter.
OX   NCBI_TaxID=251221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29082 / PCC 7421;
RX   PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA   Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA   Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA   Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA   Tabata S.;
RT   "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT   cyanobacterium that lacks thylakoids.";
RL   DNA Res. 10:137-145(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin =
CC         (6R)-L-erythro-6,7-dihydrobiopterin + H2O; Xref=Rhea:RHEA:11920,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15642, ChEBI:CHEBI:43120; EC=4.2.1.96;
CC   -!- SIMILARITY: Belongs to the pterin-4-alpha-carbinolamine dehydratase
CC       family. {ECO:0000305}.
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DR   EMBL; BA000045; BAC89586.1; -; Genomic_DNA.
DR   RefSeq; NP_924591.1; NC_005125.1.
DR   RefSeq; WP_011141644.1; NC_005125.1.
DR   AlphaFoldDB; Q7NK35; -.
DR   SMR; Q7NK35; -.
DR   STRING; 251221.35212210; -.
DR   EnsemblBacteria; BAC89586; BAC89586; BAC89586.
DR   KEGG; gvi:gsl1645; -.
DR   PATRIC; fig|251221.4.peg.1680; -.
DR   eggNOG; COG2154; Bacteria.
DR   HOGENOM; CLU_081974_4_0_3; -.
DR   InParanoid; Q7NK35; -.
DR   OrthoDB; 1862336at2; -.
DR   PhylomeDB; Q7NK35; -.
DR   Proteomes; UP000000557; Chromosome.
DR   GO; GO:0008124; F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity; IBA:GO_Central.
DR   GO; GO:0006729; P:tetrahydrobiopterin biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.30.1360.20; -; 1.
DR   HAMAP; MF_00434; Pterin_4_alpha; 1.
DR   InterPro; IPR036428; PCD_sf.
DR   InterPro; IPR001533; Pterin_deHydtase.
DR   PANTHER; PTHR12599; PTHR12599; 1.
DR   Pfam; PF01329; Pterin_4a; 1.
DR   SUPFAM; SSF55248; SSF55248; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome.
FT   CHAIN           1..92
FT                   /note="Putative pterin-4-alpha-carbinolamine dehydratase 2"
FT                   /id="PRO_0000063082"
SQ   SEQUENCE   92 AA;  10201 MW;  12E802C8BE749248 CRC64;
     MNKMTPEEIE TALKPIADWQ LSEADGATAI ERVFRFDDFV QAIAFVNKVA ERAETAGHHP
     DIHIHYNRVR LVLSTHDAGG VTSKDLEMAA AL