PHSC_ARATH
ID PHSC_ARATH Reviewed; 478 AA.
AC Q9LHN7;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Probable polyamine transporter At3g13620;
GN OrderedLocusNames=At3g13620; ORFNames=K20M4.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Probable cell membrane polyamine/proton symporter involved in
CC the polyamine uptake in cells. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
CC {ECO:0000305}.
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DR EMBL; AP002038; BAB02604.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75383.1; -; Genomic_DNA.
DR EMBL; AY056273; AAL07122.1; -; mRNA.
DR RefSeq; NP_566460.1; NM_112208.5.
DR AlphaFoldDB; Q9LHN7; -.
DR SMR; Q9LHN7; -.
DR STRING; 3702.AT3G13620.1; -.
DR TCDB; 2.A.3.12.4; the amino acid-polyamine-organocation (apc) family.
DR iPTMnet; Q9LHN7; -.
DR PaxDb; Q9LHN7; -.
DR PRIDE; Q9LHN7; -.
DR ProteomicsDB; 234906; -.
DR EnsemblPlants; AT3G13620.1; AT3G13620.1; AT3G13620.
DR GeneID; 820565; -.
DR Gramene; AT3G13620.1; AT3G13620.1; AT3G13620.
DR KEGG; ath:AT3G13620; -.
DR Araport; AT3G13620; -.
DR TAIR; locus:2086794; AT3G13620.
DR eggNOG; KOG1287; Eukaryota.
DR HOGENOM; CLU_007946_17_3_1; -.
DR InParanoid; Q9LHN7; -.
DR OMA; TQPVWVG; -.
DR OrthoDB; 621852at2759; -.
DR PhylomeDB; Q9LHN7; -.
DR PRO; PR:Q9LHN7; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LHN7; baseline and differential.
DR Genevisible; Q9LHN7; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015203; F:polyamine transmembrane transporter activity; IDA:TAIR.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0015846; P:polyamine transport; IDA:TAIR.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR044566; RMV1-like.
DR PANTHER; PTHR45826; PTHR45826; 1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..478
FT /note="Probable polyamine transporter At3g13620"
FT /id="PRO_0000418910"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 60..80
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 285..305
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..421
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 425..445
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 478 AA; 52735 MW; 38ECF79CF3FC1020 CRC64;
MAISEASKSS HELPVTTAES SGKKATAKKL TLIPLVFLIY FEVAGGPFGE EPAVQAAGPL
LAILGFLIFP FIWSIPEALI TAELSTAFPG NGGFVIWAHR AFGSFVGSMM GSLKFLSGVI
NVASFPVLCV TYLDKLFPVL ESGWPRNVCI FASTVVLSFL NYTGLAIVGY AAVVLGLVSL
SPFLVMSAMA IPKIKPHRWG SLGTKKKDWN LYFNTLFWNL NFWDNVSTLA GEVDEPQKTF
PLALLIAVIF TCVAYLIPLF AVTGAVSVDQ SRWENGFHAE AAEMIAGKWL KIWIEIGAVL
SSIGLFEAQL SSSAYQLEGM AELGFLPKFF GVRSKWFNTP WVGILISALM SLGLSYMNFT
DIISSANFLY TLGMFLEFAS FIWLRRKLPQ LKRPYRVPLK IPGLVVMCLI PSAFLVLILV
FATKIVYLIC GVMTIGAIGW YFLINYFRKT KIFEFNEVID DLDNNVNGEH PKVDDHNS
