PHSD_ARATH
ID PHSD_ARATH Reviewed; 479 AA.
AC Q9LH39;
DT 05-SEP-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Probable polyamine transporter At3g19553;
GN OrderedLocusNames=At3g19553; ORFNames=T31J18.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Probable cell membrane polyamine/proton symporter involved in
CC the polyamine uptake in cells. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Polyamine:cation symporter (PHS) (TC 2.A.3.12) family.
CC {ECO:0000305}.
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DR EMBL; AP002065; BAB01977.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76257.1; -; Genomic_DNA.
DR RefSeq; NP_188589.1; NM_112845.4.
DR AlphaFoldDB; Q9LH39; -.
DR SMR; Q9LH39; -.
DR BioGRID; 6825; 2.
DR STRING; 3702.AT3G19553.1; -.
DR PaxDb; Q9LH39; -.
DR PRIDE; Q9LH39; -.
DR ProteomicsDB; 236751; -.
DR EnsemblPlants; AT3G19553.1; AT3G19553.1; AT3G19553.
DR GeneID; 821492; -.
DR Gramene; AT3G19553.1; AT3G19553.1; AT3G19553.
DR KEGG; ath:AT3G19553; -.
DR Araport; AT3G19553; -.
DR TAIR; locus:2101520; AT3G19553.
DR eggNOG; KOG1287; Eukaryota.
DR HOGENOM; CLU_007946_17_3_1; -.
DR InParanoid; Q9LH39; -.
DR OMA; AWNFSGF; -.
DR OrthoDB; 621852at2759; -.
DR PhylomeDB; Q9LH39; -.
DR PRO; PR:Q9LH39; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LH39; baseline and differential.
DR Genevisible; Q9LH39; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015203; F:polyamine transmembrane transporter activity; IDA:TAIR.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR GO; GO:0015846; P:polyamine transport; IDA:TAIR.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR044566; RMV1-like.
DR PANTHER; PTHR45826; PTHR45826; 1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..479
FT /note="Probable polyamine transporter At3g19553"
FT /id="PRO_0000418911"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 130..150
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 160..180
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 236..256
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 275..295
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 304..324
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 355..375
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 454..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 479 AA; 52843 MW; 43E8CBD1B4E9E179 CRC64;
MGEEETIVND ENSSKPKPSP KLTLLPLVFL IFYEVSGGPF GVEDSVKSGG GPLLALLGFL
IFPLIWSIPE ALVTAELATS FPENGGYVVW ISSAFGPFWG FQEGFWKWFS GVMDNALYPV
LFLDYLKHSF PVLDHVAARV PALLVITFSL TYLNYRGLHI VGFSAVVLAV FSLCPFVVMA
LLAVPNIRPK RWLFVDTQKI NWRGYFNTMF WNLNYWDKAS TLAGEVDRPG KTFPKALFGA
VLLVMGSYLI PLMAGTGALS SSTSGEWSDG YFAEVGMLIG GVWLKGWIQA AAAMSNLGLF
EAEMSSDAFQ LLGMSEIGML PAFFAQRSKY GTPTISILCS ATGVIFLSWM SFQEIIEFLN
FLYALGMLLE FAAFVKLRIK KPDLHRPYRV PLNTFGVSML CLPPSLLVIL VMVLAAPKTF
LISGVIIVLG FCLYPFLTLV KEKQWARFIP EETRPVSGVS SESQLDEEHG DESAASLLP
