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PHT1_PSEPU
ID   PHT1_PSEPU              Reviewed;         451 AA.
AC   Q05181;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Phthalate transporter;
GN   Name=pht1;
OS   Pseudomonas putida (Arthrobacter siderocapsulatus).
OG   Plasmid PHT.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=303;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=NMH102-2;
RA   Nomura Y., Nakagawa M., Ogawa N., Harashima S., Oshima Y.;
RT   "Genes in PHT plasmid encoding the initial degradation pathway of phthalate
RT   in Pseudomonas putida.";
RL   J. Ferment. Bioeng. 74:333-344(1992).
CC   -!- PATHWAY: Xenobiotic degradation; phthalate degradation.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Phthalate
CC       permease family. {ECO:0000305}.
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DR   EMBL; D13229; BAA02509.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q05181; -.
DR   SMR; Q05181; -.
DR   TCDB; 2.A.1.14.5; the major facilitator superfamily (mfs).
DR   KEGG; ag:BAA02509; -.
DR   UniPathway; UPA00726; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0046239; P:phthalate catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.1250.20; -; 3.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Aromatic hydrocarbons catabolism; Cell membrane; Membrane; Plasmid;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..451
FT                   /note="Phthalate transporter"
FT                   /id="PRO_0000121387"
FT   TRANSMEM        119..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        170..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        260..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        331..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        354..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        386..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        416..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   451 AA;  49306 MW;  A9D3DC00B11647B6 CRC64;
     MTTTAATDAV PHLLQRSHER IEKVYRKVTL RLMTFIFVAW VLNYLDRVNI SFAQVYLKHD
     LGMSDADLRT RRKLVFHRLH RIGNTQYAYL QKIGARLTIT RIMVLWGLIS ASMAFMTTPT
     EFYIARALLG AAEAGFWPGI ILYLTYWYPG ARRARITSRF LLAIAAAGII GGPLSGWILT
     HFVDVMGMKN WQWMFILEGL PAAVMGVMAY FYLVDKPEQA KWLDDEEKSI ILDALAADRA
     GKKPVTDKRH AVLAALKDPR VYVLAAGWAT VPLCGTILNY WTPTIIRNTG IQDVLHVGLL
     STVPYIVGAI AMILIARSSD IRLERRKHFF FSIAFGALGA CLLPHVVDSA IISITCLAMI
     AVSYFGAAAI IWSIPPAYLN DESAAGGISA ISSLGQIGAF CAPIGLGWIN TVTGSLAIGL
     TIIGALVLAG GMAVLIAVPA NALSEKPLTD E
 
 
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