PHT1_PSEPU
ID PHT1_PSEPU Reviewed; 451 AA.
AC Q05181;
DT 01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1994, sequence version 1.
DT 25-MAY-2022, entry version 82.
DE RecName: Full=Phthalate transporter;
GN Name=pht1;
OS Pseudomonas putida (Arthrobacter siderocapsulatus).
OG Plasmid PHT.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=303;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=NMH102-2;
RA Nomura Y., Nakagawa M., Ogawa N., Harashima S., Oshima Y.;
RT "Genes in PHT plasmid encoding the initial degradation pathway of phthalate
RT in Pseudomonas putida.";
RL J. Ferment. Bioeng. 74:333-344(1992).
CC -!- PATHWAY: Xenobiotic degradation; phthalate degradation.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Phthalate
CC permease family. {ECO:0000305}.
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DR EMBL; D13229; BAA02509.1; -; Genomic_DNA.
DR AlphaFoldDB; Q05181; -.
DR SMR; Q05181; -.
DR TCDB; 2.A.1.14.5; the major facilitator superfamily (mfs).
DR KEGG; ag:BAA02509; -.
DR UniPathway; UPA00726; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0046239; P:phthalate catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.20.1250.20; -; 3.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Aromatic hydrocarbons catabolism; Cell membrane; Membrane; Plasmid;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..451
FT /note="Phthalate transporter"
FT /id="PRO_0000121387"
FT TRANSMEM 119..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 260..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 331..342
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 386..408
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 416..439
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 451 AA; 49306 MW; A9D3DC00B11647B6 CRC64;
MTTTAATDAV PHLLQRSHER IEKVYRKVTL RLMTFIFVAW VLNYLDRVNI SFAQVYLKHD
LGMSDADLRT RRKLVFHRLH RIGNTQYAYL QKIGARLTIT RIMVLWGLIS ASMAFMTTPT
EFYIARALLG AAEAGFWPGI ILYLTYWYPG ARRARITSRF LLAIAAAGII GGPLSGWILT
HFVDVMGMKN WQWMFILEGL PAAVMGVMAY FYLVDKPEQA KWLDDEEKSI ILDALAADRA
GKKPVTDKRH AVLAALKDPR VYVLAAGWAT VPLCGTILNY WTPTIIRNTG IQDVLHVGLL
STVPYIVGAI AMILIARSSD IRLERRKHFF FSIAFGALGA CLLPHVVDSA IISITCLAMI
AVSYFGAAAI IWSIPPAYLN DESAAGGISA ISSLGQIGAF CAPIGLGWIN TVTGSLAIGL
TIIGALVLAG GMAVLIAVPA NALSEKPLTD E