ID   PHTF2_CHICK             Reviewed;         752 AA.
AC   Q5ZKN3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Protein PHTF2 {ECO:0000305};
GN   Name=PHTF2; ORFNames=RCJMB04_9p2;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ720051; CAG31710.1; -; mRNA.
DR   RefSeq; NP_001006226.1; NM_001006226.1.
DR   AlphaFoldDB; Q5ZKN3; -.
DR   STRING; 9031.ENSGALP00000038897; -.
DR   PaxDb; Q5ZKN3; -.
DR   GeneID; 417728; -.
DR   KEGG; gga:417728; -.
DR   CTD; 57157; -.
DR   VEuPathDB; HostDB:geneid_417728; -.
DR   eggNOG; ENOG502QQGQ; Eukaryota.
DR   InParanoid; Q5ZKN3; -.
DR   OrthoDB; 710715at2759; -.
DR   PhylomeDB; Q5ZKN3; -.
DR   PRO; PR:Q5ZKN3; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR039775; PHTF1/2.
DR   InterPro; IPR021980; PHTF1/2_N.
DR   PANTHER; PTHR12680; PTHR12680; 1.
DR   Pfam; PF12129; Phtf-FEM1B_bdg; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..752
FT                   /note="Protein PHTF2"
FT                   /id="PRO_0000318511"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        464..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        520..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        601..621
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        635..655
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        727..747
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          6..153
FT                   /note="PHTF"
FT                   /evidence="ECO:0000255"
FT   REGION          173..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          227..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          273..371
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        344..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        296
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        664
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
FT   CARBOHYD        723
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00498"
SQ   SEQUENCE   752 AA;  85452 MW;  E1E224D2E7F86AB6 CRC64;
     MASKVTDARD WYQKKIGAYD QQIWEKSVEQ REIKGLRNKP KKTGHVKPDL IDVDLVRGSA
     FAKAKPESPW TSLTRKGIVR VVFFPFFYRW WLQVTSRVIF FWLLVLYLLQ VAAVVLFCTA
     QSPHNIPLTE VIGPIWLMLL LGTVHCQIVS TRTPKPPPST GVKRRRKLRK AAHLEVHREG
     DGSSTTDNTQ EGTVQSYGTS TSYSIGAVFR DIWHAAFFLS GSKKAKNSID KSTETDNGYV
     SLEGKKTGKS SEECAQAQER LCEVIKPEES GWSTTTMRET FGTPSHHKET HRTVTNLSDE
     VSSEEGPETG YSLRRNVERT SSDGTLRNRK SHHYKKHYPL EDTPKSGTSC SSRCSSSRQD
     SESTRPESET EDVWEDLLHC AECHSSCTSE TDVESPQMNP CVKKEYRDDP FHQSHLPWIH
     SLNPGLEKIS AIVWEGNDCK KADMSVLEIS GMIMNRVNSY IPGIGYQIFG NIISLILGLM
     PFVFRLSQAK DLEQLAAHSA TELCITAFGS NGDILVLSMV VISFVVRVSL VWIFFFLLCV
     AERTYKQRLL FAKLFGHLTS ARRARKSEVP HFRLKKVQNI KMWLSLRSYL KRRGPQRSVD
     VIVSSAFLLT ISVVFICCAQ LLHMHEIFLD CHYNWELVIW CISLTLFLLR FVTLGSETSK
     KYSNTSILLT EQINLYLKME KKPNKKEELT LVNNVLKLAT KLLKELDSPF RLYGLTMNPL
     LYNITQVVIL SAVSGVISDL LGFNLKLWKI KS