PHY2_CERPU
ID PHY2_CERPU Reviewed; 1121 AA.
AC Q39557;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Phytochrome 2;
GN Name=PHY2;
OS Ceratodon purpureus (Fire moss) (Dicranum purpureum).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta;
OC Bryophytina; Bryopsida; Dicranidae; Pseudoditrichales; Ditrichaceae;
OC Ceratodon.
OX NCBI_TaxID=3225;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Hughes J.E., Lamparter T., Mittmann F.;
RT "CERPU;PHY0;2, a 'normal' phytochrome in Ceratodon.";
RL (er) Plant Gene Register PGR96-067(1996).
CC -!- FUNCTION: Regulatory photoreceptor which exists in two forms that are
CC reversibly interconvertible by light: the Pr form that absorbs
CC maximally in the red region of the spectrum and the Pfr form that
CC absorbs maximally in the far-red region. Photoconversion of Pr to Pfr
CC induces an array of morphogenic responses, whereas reconversion of Pfr
CC to Pr cancels the induction of those responses. Pfr controls the
CC expression of a number of nuclear genes including those encoding the
CC small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B
CC binding protein, protochlorophyllide reductase, rRNA, etc. It also
CC controls the expression of its own gene(s) in a negative feedback
CC fashion.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- PTM: Contains one covalently linked phytochromobilin chromophore.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytochrome family. {ECO:0000305}.
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DR EMBL; U56698; AAB67863.1; -; Genomic_DNA.
DR PIR; S58130; S58130.
DR AlphaFoldDB; Q39557; -.
DR SMR; Q39557; -.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR GO; GO:0017006; P:protein-tetrapyrrole linkage; IEA:InterPro.
DR GO; GO:0009585; P:red, far-red light phototransduction; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd16932; HATPase_Phy-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.270; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013654; PAS_2.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR044767; Phy_HATPase-like.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR013516; Phyto_chromo_BS.
DR InterPro; IPR001294; Phytochrome.
DR InterPro; IPR012129; Phytochrome_A-E.
DR InterPro; IPR013515; Phytochrome_cen-reg.
DR InterPro; IPR043150; Phytochrome_PHY.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08446; PAS_2; 1.
DR Pfam; PF00360; PHY; 1.
DR PIRSF; PIRSF000084; Phytochrome; 1.
DR PRINTS; PR01033; PHYTOCHROME.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55785; SSF55785; 3.
DR SUPFAM; SSF55874; SSF55874; 1.
DR TIGRFAMs; TIGR00229; sensory_box; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS00245; PHYTOCHROME_1; 1.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 3: Inferred from homology;
KW Chromophore; Photoreceptor protein; Receptor; Repeat; Sensory transduction;
KW Transcription; Transcription regulation.
FT CHAIN 1..1121
FT /note="Phytochrome 2"
FT /id="PRO_0000171971"
FT DOMAIN 214..393
FT /note="GAF"
FT DOMAIN 608..679
FT /note="PAS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 742..813
FT /note="PAS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 893..1113
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT BINDING 319
FT /ligand="phytochromobilin"
FT /ligand_id="ChEBI:CHEBI:189064"
FT /note="covalent, via 1 link"
FT /evidence="ECO:0000250"
SQ SEQUENCE 1121 AA; 124127 MW; FAA0DB62426EA32E CRC64;
MSAPKKTYSS TTSAKSKHSV RVAQTTADAA LEAVYEMSGD SGDSFDYSKS VGQSAESVPA
GAVTAYLQRM QRGGLIQTFG CMVAVEEPNF CVIAYSENAS EFLDLMPQAV PSMGEMDVLG
IGTDIRTLFT PSSGAALEKA AATQDISLLN PITVHCRRSG KPLYAIAHRI DIGIVIDFEA
VKMNDVSVSA AGALQSHKLA AKAITRLQAL PGGDIGLLCD TVVEEVRELT GYDRVMAYKF
HEDEHGEVVA EIRRMDLEPY LGLHYPATDI PQASRFLFMK NRVRVIADCC ASPVKLIQDP
DIKQPVSLAG STLRAPHGCH AQYMGNMGSI ASLVMAVIIN DNEEDSRGAI QRGRKLWGLV
VCHHTSPRTV PFPLRSACEF LMQVFGMQLN MEVELAAQLR EKHILRTQTL LCDMLLRDAP
IGIVSQTPNI MDLVKCDGAA LYYGKRFWLL GTTPTENQIK DIAEWLLEYH KDSTGLSTDS
LADANYPGAH LLGDAVCGMA AAKITAKDFL FWFRSHTAKE VKWGGAKHDP AEKDDGRKMH
PRSSFKAFLE VVKRRSLPWE DVEMDAIHSL QLILRGSFQD IDDSDTKTMI HARLNDLKLH
GMDELSVVAN EMVRLIETAT APILAVDSTG MINGWNAKIA HVTGLPVSEA MGRSLVKDLV
LDESVVVVER LLYLASQGEE EQNVEIKLKT FGTQTEKEAV ILIVNACSSR DVSDSVVGVC
FVGQDVTGQK MFMDKFTRIQ GDYKTIVKNP HPLIPPIFGG DEYGYCFEWN PAMEALTGWK
HDEVVGKLLV GEIFGMEMMC CRLKSQDSMT KFMISLNNAM DGTNTDKFSF SFCNREGKFV
EALLSTNKRT NADGVITGVF CFLQIASSEL QQALTVQRAT EKVAIAKLKE LAYIRQEIKN
PLCGITFTRQ LLEDTDLSDD QKQFLDTSAV CEQQLQKVLN DMDLESIEDG YLELDTAEFE
MGTVMDAVIS QGMTTSREKG LQIIRETPRE ISTMRLFGDQ IRLQQVLSDF LINAIRFTPS
SEGWVKIKVV PTRKRLGGNV HVMHLEFRVS HPGGGLPDEL VLEMYDRAKG MTQEGLGLNM
CRKLVRLMNG DVQYVRENAQ CYFVVYVELP MAQRDDAASQ M
