PHYA_LATSA
ID PHYA_LATSA Reviewed; 1124 AA.
AC P93673;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Phytochrome type A;
GN Name=PHYA;
OS Lathyrus sativus (White vetchling).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Fabeae; Lathyrus.
OX NCBI_TaxID=3860;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. C-24;
RA Gutierrez-Marcos J.F., Vences-Benito F.J.;
RL Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Regulatory photoreceptor which exists in two forms that are
CC reversibly interconvertible by light: the Pr form that absorbs
CC maximally in the red region of the spectrum and the Pfr form that
CC absorbs maximally in the far-red region. Photoconversion of Pr to Pfr
CC induces an array of morphogenic responses, whereas reconversion of Pfr
CC to Pr cancels the induction of those responses. Pfr controls the
CC expression of a number of nuclear genes including those encoding the
CC small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B
CC binding protein, protochlorophyllide reductase, rRNA, etc. It also
CC controls the expression of its own gene(s) in a negative feedback
CC fashion.
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- PTM: Contains one covalently linked phytochromobilin chromophore.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the phytochrome family. {ECO:0000305}.
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DR EMBL; U84970; AAB47994.1; -; Genomic_DNA.
DR AlphaFoldDB; P93673; -.
DR SMR; P93673; -.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0009881; F:photoreceptor activity; IEA:UniProtKB-KW.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0009584; P:detection of visible light; IEA:InterPro.
DR GO; GO:0017006; P:protein-tetrapyrrole linkage; IEA:InterPro.
DR GO; GO:0009585; P:red, far-red light phototransduction; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.450.270; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; -; 1.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013654; PAS_2.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR016132; Phyto_chromo_attachment.
DR InterPro; IPR013516; Phyto_chromo_BS.
DR InterPro; IPR001294; Phytochrome.
DR InterPro; IPR012129; Phytochrome_A-E.
DR InterPro; IPR013515; Phytochrome_cen-reg.
DR InterPro; IPR043150; Phytochrome_PHY.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF08446; PAS_2; 1.
DR Pfam; PF00360; PHY; 1.
DR PIRSF; PIRSF000084; Phytochrome; 1.
DR PRINTS; PR01033; PHYTOCHROME.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55785; SSF55785; 3.
DR SUPFAM; SSF55874; SSF55874; 1.
DR TIGRFAMs; TIGR00229; sensory_box; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS00245; PHYTOCHROME_1; 1.
DR PROSITE; PS50046; PHYTOCHROME_2; 1.
PE 3: Inferred from homology;
KW Chromophore; Photoreceptor protein; Receptor; Repeat; Sensory transduction;
KW Transcription; Transcription regulation.
FT CHAIN 1..1124
FT /note="Phytochrome type A"
FT /id="PRO_0000171973"
FT DOMAIN 218..401
FT /note="GAF"
FT DOMAIN 617..687
FT /note="PAS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 750..821
FT /note="PAS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 901..1120
FT /note="Histidine kinase"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00107"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 323
FT /ligand="phytochromobilin"
FT /ligand_id="ChEBI:CHEBI:189064"
FT /note="covalent, via 1 link"
FT /evidence="ECO:0000250"
SQ SEQUENCE 1124 AA; 124251 MW; C7A6995BAA2C28EA CRC64;
MSTTRPSQSS NNSGRSRNSA RIIAQTTVDA KLHATFEESG SSFDYSSWVR VSGSVDGDQQ
PRSNKVTTAY LNHIQRGKQI QPFGCLLALD EKTCKVVAYS ENAPEMLTMV SHAVPSVGDH
PALGIGTDIR TVFTAPSASA LQKALGFAEV SLLNPILVHC KTSGKPFYAI IHRVTGSLII
DFEPVKPYEV PMTAAGALQS YKLAAKAITR LQSLASGSME RLCDTMVQEV FELTGYDRVM
AYKFHEDDHG EVIAEIAKPG LEPYLGLHYP ATDIPQAARF LFMKNKVRMI VDCNAKHVKV
LQDEKLPFDL TLCGSTLRAP HSCHLQYMAN MDSIASLVMA VVVNDSDEDG DSADAVLPQK
KKRLWGLVVC HNTTPRFVPF PLRYACEFLA QVFAIHVNKE IELEYQILEK NILRTQTLLC
DMLMRDAPLG IVSQSPNIMD LVKCDGAALF YRNKLWLLGA TPTEYQIREI ALWMSEYHTD
STGLSTDSLL DAGFPGALSL SDTVCGMAAV RITSKDIVFW FRSHTAAEIR WGGAKHEPGE
QDDGRKMHPR SSFKAFLEVV KARSVPWKDF EMDAIHSLQL ILRNASKDTD IIDLNTKAIN
TRLNDLKIEG MQELEAVTSE MVRLIETATV PILAVDVDGT VNGWNIKIAE LTGLPVGEAI
GKHLLTLVED SSTDIVKKML NLALQGEEEK NVQFEIKTHG DQVEFGPISL IVNACASRDL
RENVVGVCFV AQDITAQKTV MDKFTRIEGD YKAIVQNPNQ LIPPIFGTDE FGWCCEWNAA
MIKLTGWKRE EVMDKMLLGE VFGTQMSCCR LKNQEAFVNF GIVLNKAMTG LETEKVAFGF
FSRKGKYVEC LLSVSKKIDA EGLVTGVFCF LQLASPELQQ ALHIQRLSEQ TALKRLKVLT
YMKRQIRNPL AGIVFSSKML EGTDLETEQK QIVNTSSQCQ RQLSKILDDS DLDGIIDGYL
DLEMAEFTLH EVLVTSLSQV MNRSNTKGIR IANDVAEHIA KESLYGDSLR LQQVLADFLL
ISINSTPNGG QVVIASSLTK EQLGKSVHLV NLELSITHGG SGVPEAALNQ MFGNNVLESE
EGISLHISRK LLKLMNGDVR YLKEAGKSSF ILSVELAAAH KLKG
